ID A0A1U7V5D9_NICSY Unreviewed; 631 AA.
AC A0A1U7V5D9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Vacuolar-sorting receptor 3-like {ECO:0000313|RefSeq:XP_009760191.1};
GN Name=LOC104212583 {ECO:0000313|RefSeq:XP_009760191.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009760191.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009760191.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009760191.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00029430}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00029430}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004614}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Prevacuolar compartment membrane
CC {ECO:0000256|ARBA:ARBA00043947}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00043947}.
CC -!- SIMILARITY: Belongs to the VSR (BP-80) family.
CC {ECO:0000256|ARBA:ARBA00007038}.
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DR RefSeq; XP_009760191.1; XM_009761889.1.
DR AlphaFoldDB; A0A1U7V5D9; -.
DR STRING; 4096.A0A1U7V5D9; -.
DR GeneID; 104212583; -.
DR KEGG; nsy:104212583; -.
DR eggNOG; ENOG502QSX2; Eukaryota.
DR OrthoDB; 305396at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd02125; PA_VSR; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF02225; PA; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Receptor {ECO:0000313|RefSeq:XP_009760191.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..631
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010568920"
FT TRANSMEM 572..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 504..518
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
SQ SEQUENCE 631 AA; 69945 MW; 6DF58F27FD2BE40F CRC64;
MGVSKIWKAT IFLGFLWLNL LFQSVVGRFV VEKNSLRVVS PDDIKGTYDS AIGNFGIPQY
GGSLPGTVVY PKGNQKGCRN FDDSGISFKS KSGAMPTFVL VDRGDCFFAL KVWNAQNAGA
AAVLVADDVD ERLITMDTPE ADGSSAKYIE NITIPSALIE KSFAEKLKKA VSAGEMVNVN
LDWREAVPHP DDRVEYELWT SSNDECGFKC DMLMKYVKDF KGAAQILEKG GYTQFTPHYI
TWYCPQAFTV SKQCKSQCIN HGRYCAPDPE QDFSTGYEGK DVVIENLRQL CVFKVANETK
KPWVWWDYVT DFQIRCPMKE KKYNKECADA VIKSLGLDLR KIEKCMGDPN ADEDNPVLKE
EQNAQVGKGT RGDVTILPTL VVNNRQYRGK LEKGAVLKAI CAGFEETTEP AVCLSDDVET
NECRDNNGGC WQDKAANITA CKDTFRGRVC ECPVVDGVQF KGDGYSSCTA SGPGRCKLNN
GGCWHDTRDG HTYSACVDNE EGKCSCPPGF KGDGVKSCDD IDECKEKKAC QCPECSCKNT
WGSYECSCSG DLLYIRDHDT CISKRAREVK SAWAAVWAIL IGLAMAGGGA YLVYKYRLRS
YMDSEIRAIM AQYMPLDSQN EVPNHVSDER A
//
