ID A0A1U7V5Q3_NICSY Unreviewed; 404 AA.
AC A0A1U7V5Q3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Probable sodium-coupled neutral amino acid transporter 6 isoform X2 {ECO:0000313|RefSeq:XP_009763497.1};
GN Name=LOC104215411 {ECO:0000313|RefSeq:XP_009763497.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009763497.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009763497.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009763497.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_009763497.1; XM_009765195.1.
DR AlphaFoldDB; A0A1U7V5Q3; -.
DR GeneID; 104215411; -.
DR OrthoDB; 4133660at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0031090; C:organelle membrane; IEA:UniProt.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF613; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 5-LIKE ISOFORM X1; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022970}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..401
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 404 AA; 44740 MW; A649454ED3435A3A CRC64;
MDPSRTGTSA DVPLLSQQNS PTRENNQWMI WRAVFNVSTT IIGAGIMSIP ATLKVLGVIP
AFMLIVLVAI LVEITVNFML RATYAGQSTT YAGLMKENFG KTGSLAVQIC VMITTLGCLI
MYLIIIGDVF SGKGEHLGIL QEWFGIHWWN SRYLSILFTV LFVVLPLVLY RRVESLWFSS
AVAIILAIVF VGICTVMAFI AIAKGQIVRP RMLPELNSTK SFFNLFTAIP VIVTAFAFHF
NVHPIGIELG KPGAMTTAVK ISLVICAAIY FSIGIFGYLL FGDSINADIL VNFGMSSGSV
AISPILNDVV RLSYALHLML VFPLLNFSLR ANIDELIFPK KEHLSTDTKR FMYLTLILLA
LSYLVAIAIP SIWYIYQFMG STSNACLAFI FPEMFMVYLQ GKTR
//
