ID A0A1U7V9Q1_NICSY Unreviewed; 724 AA.
AC A0A1U7V9Q1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Protein VAC14 homolog {ECO:0000313|RefSeq:XP_009764762.1};
GN Name=LOC104216426 {ECO:0000313|RefSeq:XP_009764762.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009764762.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009764762.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009764762.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the VAC14 family.
CC {ECO:0000256|ARBA:ARBA00010225}.
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DR RefSeq; XP_009764762.1; XM_009766460.1.
DR AlphaFoldDB; A0A1U7V9Q1; -.
DR STRING; 4096.A0A1U7V9Q1; -.
DR GeneID; 104216426; -.
DR KEGG; nsy:104216426; -.
DR eggNOG; KOG0212; Eukaryota.
DR OrthoDB; 5481081at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR026825; Vac14.
DR InterPro; IPR021841; VAC14_Fig4p-bd.
DR PANTHER; PTHR16023:SF1; PROTEIN VAC14 HOMOLOG; 1.
DR PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12755; Vac14_Fab1_bd; 1.
DR Pfam; PF11916; Vac14_Fig4_bd; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT REPEAT 94..129
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 431..610
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT REGION 700..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 81648 MW; 3F00A20E530153EE CRC64;
MATTEALSVI PASVLRNLSD KLYEKRKNAA LELEGIVKQL AVAGDHDKVT AVIHLLTQEY
TYSPQANHRK GGLIGLAAVT VGLTSEAAQH LEQIVPPVLN SFSDQDSRVR YYACEALYNI
AKVVRGDFIV FFNQIFDALC KLSADSDANV QSAAHLLDRL VKDIVTESDQ FSIEEFIPLL
RERMNVLNPY VRQFLVGWIT VLDSVPDIDM LGFLPDFLDG LFNMLSDNSH EIRQQADSAL
SEFLQEIKNS PSVDYGRMAE ILVQRAGSQD EFTRLTAVTW INEFVKLGGE QLVPYYADIL
GAILPCISDK EEKIRVVARE TNEELRGIET DPAEGFDVGA ILSIAQRQLS SEWEATRIEA
LHWMSTLLNR HRSEVLVFLN DILDSLLKAL SDPSDEVVLL VLEVHACIAE DPQHFRQLVV
FLIHNFQLDH SLLEKRGALI IRQLCFLLDA ERVYRELSTI LEGESDFDFA SIMVQALNLI
LLTSSELSDL RDLLKQSLVN ADGKNLFLSL YASWCHSPMA IISLCLLAQA YQHASSVIHS
LVEEDINVKF LVQLDKLIHL LETPTFAYLR LQLLEPGRYI WLLKALYGLL MLLPQQSAAF
KVLRTRLKTV PSYSFKEERF RRTSGIPYSQ FNYGGGGSQI SEDGDLNENL HDMHSGINFD
LKLQQLQQIQ KQHHLHSKSQ TQSRFVSTSW MKEVQIAEES KRAASELNRP PSRSSGRGLG
QLQL
//
