ID A0A1U7VB97_NICSY Unreviewed; 1351 AA.
AC A0A1U7VB97;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Uncharacterized protein LOC104211704 {ECO:0000313|RefSeq:XP_009759100.1};
GN Name=LOC104211704 {ECO:0000313|RefSeq:XP_009759100.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009759100.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009759100.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009759100.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR RefSeq; XP_009759100.1; XM_009760798.1.
DR GeneID; 104211704; -.
DR KEGG; nsy:104211704; -.
DR eggNOG; ENOG502QWDY; Eukaryota.
DR OrthoDB; 3900892at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 2.
DR Gene3D; 3.30.430.20; Gnk2 domain, C-X8-C-X2-C motif; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27002:SF844; CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 27-RELATED; 1.
DR PANTHER; PTHR27002; RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE SD1-8; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 2.
DR Pfam; PF01657; Stress-antifung; 4.
DR SMART; SM00220; S_TKc; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR PROSITE; PS51473; GNK2; 4.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 966..987
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..138
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 144..252
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 353..628
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 710..812
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 818..926
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 1028..1303
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 263..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1351 AA; 151132 MW; 22BB0268F484C797 CRC64;
MWMGKTDMSF LTWLGIILIF HFYYLFYLSI AQPNFAFQSP CEGNETEYSP NGAYGTNLNT
VLSSLSRNID SDGFYNTSIG QDPDKVSVIA QCRGDVDLQT CRDCIKNATR LILELCPQKK
SAFGIYDKCL IRYSNESFIG TVSTDPQKIY YYNQNFSNPQ LFFNRYLTPV LENLRSRASE
GGKRKFAANI TNAPDFARIY VLVQCTADLS ADDCFNCLTT GYQTLPSCEC YAKRGNYYLM
PSCIIRYEPY SFFNESFAEA PPSPPPASLP LPPPASPPLP QPGKDDKTAR TVIIIVVPTV
TVVIFVVCIP VILMKRRKRK LVNKRESIHV DDISTAESLQ YDFSTIRAAT NNFSDVNKLG
QGGFGPVYKG KLPNGQEVAV KRLSADSGQG DLEFKNEVLL VARLQHRNLV RLLGFCLDGI
ERLLVYEFVP NASLDHFLFD SVKRRQLDWE RRSRIIGGIA RGILYLHEDS RLRIIHRDLK
ASNVLLDAEM NPKISDFGMA RLFTLDETQG STSRIVGTYG YMAPEYAMHG QFSVKSDVFS
FGVLVLEILS GQRNTSFRNG ESVEDLLSYA WSNWREGTTT NFIDPMLRGS TGLVRDIVRC
IHIALLCVQE NVANRPTMAA VVLMLSSLSL SLPVPSGPAY YMHNDISPET SLVQEYNSRM
SDSREPAKSK SISSSRNEAS ITELYPRLVI LIFQFYFFFE LSIAQPSFRS YACADYTDKT
EFSPNSAYDT NLNTLLSTLS RDMDSYGFYN TSIGQNPDKV SVVAQCRGDV ESQTCRNCIT
NATLKILEVC PYKKAGFGYY DDCTLRYSNE SIIGTVSNNP LVFIFNTANV SSPDVFMQED
LRTLLESLQS KASAGGKRKF ARNSTRGPDF QTIHALVQCT ADLSAEECFN CLRTGYESLP
SCPCYGKRAA TVLMPSCNFI FQVNPFSNKL PTEAPPPLWP PPPSPLWQSP PPLPPSPPPT
VTARTVIITV VPTVTVVILI VCTFVILRKR QKRKHLLNPI ESIHGDDTTT AESLQYDFSA
IQAATDNFSN ANKLGQGGFG PVYKGKLPNG QEVAVKRLSV GSGQGDLEFK NEVLLVARLQ
HRNLVRLRGF CLDGTERLLV YEFVPNASLD HFLFDSVKRR QLDWEKRYKI IGGIAKGILY
LHEDSRLRII HRDLKASNVL LDADMNPKIS DFGMARLFTL DETQGNTRRI VGTYGYMAPE
YAMHGQFSVK SDVFSFGVLV LEILSGQRNT RFRNGESVED LLSYAWTNWR EGTSSNLIDP
ILRGSSGIVR DITRCIHIAL LCVQQNAADR PTMAAVVLML SSLSLSLPVP SGPAYSMHNV
GNPENSLIQE YNSRMSRSSQ NEVSITELYP R
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