ID   A0A1U7VJ31_NICSY        Unreviewed;      1467 AA.
AC   A0A1U7VJ31;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Abnormal spindle-like microcephaly-associated protein homolog isoform X2 {ECO:0000313|RefSeq:XP_009762354.1};
GN   Name=LOC104214386 {ECO:0000313|RefSeq:XP_009762354.1};
OS   Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009762354.1};
RN   [1] {ECO:0000313|Proteomes:UP000189701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA   Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA   Peitsch M.C., Ivanov N.V.;
RT   "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT   tomentosiformis.";
RL   Genome Biol. 14:R60.1-R60.17(2013).
RN   [2] {ECO:0000313|RefSeq:XP_009762354.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_009762354.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_009762354.1; XM_009764052.1.
DR   GeneID; 104214386; -.
DR   OrthoDB; 53079at2759; -.
DR   Proteomes; UP000189701; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.190; -; 8.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR   Pfam; PF00612; IQ; 12.
DR   SMART; SM00185; ARM; 1.
DR   SMART; SM00015; IQ; 16.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR   PROSITE; PS50176; ARM_REPEAT; 1.
DR   PROSITE; PS50096; IQ; 10.
PE   4: Predicted;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          1304..1351
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ   SEQUENCE   1467 AA;  167096 MW;  E02D31CD3859CFD0 CRC64;
     MEQKKASQTS CIPSPFQDFP FKEISNFKTP KPSRYAAKFS SPSPTPIHCQ AEFFTASKTT
     PVSSVRRRGS MKPSAVKSSA TARRLKAFEL EQTKSARKAL ISKERSLKSL AKSLTVWLNF
     LFENPSSCGC DVSSFTGGFE TSNRLPCVAG NGKRRESGAG HNTVGVDVLW RGPKRQRHLS
     SNFEDGETTA FSDSMFSGLK ASLTDICSFD DLKERMSGYL SLGSCKEVFV TMTQVTKTID
     EGRLKMRAHC PMVTDVGMKE KALRTLMCYN PVWLRIGLYI LLGGDTLLPN GDVNSDQEIA
     FLKMVLDKQF FSHVGLAKTY AYNKLVEGLY RPGYYEKLGN IVLKRFLLLV LILDRVKTQS
     SLPLKYGIDA QDGGSPLLFS LQSDAKSSRQ LINKFLSSDV MHGEGNLLAH LVIVGYKVTY
     QQNPLLEYHF GVADLFKDLQ DGIRLCRAIQ LLQHDPSILS LPLLINKELF SEEISKIRGV
     VEQNSSSCNH LDMLLNWIRA ICESYDLKVE NFSSFVDGKA MWCLLDYYFR KDNRCSCSYQ
     ALSEAKEEVS IVSVVDYTDA VHNFILSQKL PLLLGRFPEV LQVSDILETN GACNGQSVII
     LLVFLSFQLL VRRNKDQLNF HKLLGFNCQS PERRRLSTDQ WFMHPEAAVD PEQNDDKDVA
     RNFKAVMSWW QEMAQQNNKC TSKETSSSLV KWSFTSKRTN DTQKENAAKV IQSHFRQSVQ
     RRKYLRIRNA VCILQAAVQA WLRVKKEQSI QFFGSQTYLA SLCGARNCSE NLEKHAAFVV
     DRHAFLKLRR SVRIIQRATR DWISRRHVTG DASPQDLSAQ TLIDAAIVIQ KCIRGWIVRS
     SLVSTDQSPT VPKECEENIN AAVAIQHASK EYTLSSPLHS QHFAATKIQS YYHGWLMRKK
     FVDQKQAAIK IQSIFQSARC LRDFHCYKQE ALSAIAIQAY VRKRIAQREV YRRKSQIIMI
     QSHCRGWLTR KRLLIEKEAV IKIQTAIRSM KYRKAFLRQR HATLEIQRFA RGAITRKSLL
     GASCYSNISK LGDQTLALKI LLQAVLKLQR WWRGKLLHEQ RTKAALVIQS HVRGWTARQS
     ASRNKHQIIV IQSHCRGWLT RKRLLIEKEA VIKIQTAIRS MKYRKAFLRQ RHATLEIQRF
     ARGAITRMSL LGASCYSNIS KLGYQTLALK IQLQSVLKLQ RWWRGKLLHE QRTKAALVIQ
     SHVRGWTARQ SASRNKHRII VIQAYMKGYL ARKDLRGQLL DLRLRVQKSA ANVNDGMRII
     NRLVAALSEL LNMRSVSDIL RICATLNMAT QHSQKCCEEL VAAGAVGTLL KLISSLSRSL
     PDQEVTKHAL STLRNLSRYP HLINVLIDSC GSVETILREF LRNKEEGYFI ASDLLKKIFT
     EKTGVEAVHK LPALLRRLRD HVEELSRKAK PDKWSRTPQP HARKELDKRL REAVEILELI
     KVSLGNPTRR LSYKGQLQVA VHLTKVG
//