ID A0A1U7VLW4_NICSY Unreviewed; 601 AA.
AC A0A1U7VLW4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Serine/threonine-protein kinase CTR1 {ECO:0000313|RefSeq:XP_009765956.1};
GN Name=LOC104217413 {ECO:0000313|RefSeq:XP_009765956.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009765956.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009765956.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009765956.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_009765956.1; XM_009767654.1.
DR AlphaFoldDB; A0A1U7VLW4; -.
DR STRING; 4096.A0A1U7VLW4; -.
DR GeneID; 104217413; -.
DR KEGG; nsy:104217413; -.
DR eggNOG; KOG0192; Eukaryota.
DR OrthoDB; 1216705at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13999; STKc_MAP3K-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR23257:SF813; SERINE_THREONINE-PROTEIN KINASE EDR1; 1.
DR Pfam; PF14381; EDR1; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_009765956.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 325..583
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 235..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 352
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 601 AA; 67009 MW; 72A0A8A7539AB4A6 CRC64;
MDPYVWIVCS DLQESARIPS IESLRAVDPS VVPSLEVILI DRRSDPSLKE LQNRIHNLSP
SCITTKEVVD QLAKVVCNHM GGTASAGEDE LVPMWKECSD DLKDCLGSVV LPIGSLSIGL
CRHRALLFKV LADIIDLPCR IAKGCKYCNR ADASSCLVRF GLDREYLVDL IGDPGCLCEP
DSSLNGPSSI SISSPLRFPR FREVEPTIDF RSFAKQYFSD CQSLNLVFED PSAGAAVDGD
SGQTDRNNME RNSVVPSSSN HDEISRLPVP PVGHGDTQPL MALSDPRGRG NDMRFLDGGS
QLVPAKQSRD LALEVEEFDI PWEDLVLKER IGAGSFGTVH RADWNGSDVA VKILMEQDFH
AERFKEFLRE VAIMKRLRHP NIVLFMGAVT QRPNLSIVTE YLSRGSLYRL LHKPGAREVL
DERRRLSMAY DVAKGMNYLH KRNPPIVHRD LKSPNLLVDK KYTVKVCDFG LSRLKANTFL
SSKSAAGTPE WMAPEVLRDE PSNEKSDVYS FGVILWELAT LQQPWSNLNP AQVVAAVGFK
GKRLEIPRDL NPQVASIIEA CWAKEPWKRP SFSVIMDMLR PLIKPPVTPP QPGRTDMQLL
T
//
