ID A0A1U7VVC5_NICSY Unreviewed; 719 AA.
AC A0A1U7VVC5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Target of Myb protein 1-like {ECO:0000313|RefSeq:XP_009766354.1};
GN Name=LOC104217742 {ECO:0000313|RefSeq:XP_009766354.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009766354.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009766354.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009766354.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_009766354.1; XM_009768052.1.
DR AlphaFoldDB; A0A1U7VVC5; -.
DR SMR; A0A1U7VVC5; -.
DR STRING; 4096.A0A1U7VVC5; -.
DR GeneID; 104217742; -.
DR KEGG; nsy:104217742; -.
DR eggNOG; KOG1087; Eukaryota.
DR OrthoDB; 620063at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898:SF2; TARGET OF MYB PROTEIN 1; 1.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 37..166
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 209..297
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 174..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..502
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 79100 MW; B5A0D0D2D038A830 CRC64;
MLSPDWRKKR MISSLGAASS SSSSSSSSSA AVRVEKATSE FLIGPDWTIN IDICDTINSN
HWLAKDVVKA VKKRLQHKNP KVQLLSLTLL ETMVKNCGDN VHFQIAERSI LQDMVKIVKK
KTDMHVRDKV LVLLDSWQEA FGGPGGKYPQ YYWAYEELRR AGVEFPKRSF DTAPIFTPPV
THPAPRQPQP GYGMPSNSST RLDEAMAADM ENLSLSSINS MKEVADLLAD MLQAVTPGDR
LAVQDEVIVD LVYQCRSNQK KLMQMLTTTG DEELLAQGLE LNDNLQMVLA KHDAIASGSP
LPTEVPNNNI SAREMHDPSL KPAEVEPPTP AADAKPSAPV LAPTAGQIDE EEDEEDDFAQ
LARRHSKTSP AAQTSEGMVS AYNSNSTGES LDPVTSNALI LRDPPPTAMP TKEQDIIDLL
SLTLSSSIYP ETPQNSASAN HSTHQEPVAS TTQGNPYASQ AYLGYQDQSF NSYVAPWAQT
QPQPQPQSQS QPQFPPQFQP QSQPQSQPQY HHQFQTPTQA QFQTQAQAQP QAQPLHQPHP
RPQPQYPQES SLQSQHTSQQ LPQCPLQTEL NQQPRTQLEL HPQPQQLPPR AQTQFPQYSA
YPPPPWASTP GYFSNLNHST RPSYMYSTPQ NTSMPLQGPR PVQNVNSIPT MGSNGVAING
DAQIRPSPKT TSSTAGQKPF IPSYRLFEDL NVFGNGDQRH NSSSGVSGTN SQSMVGGRK
//
