ID A0A1U7WF58_NICSY Unreviewed; 291 AA.
AC A0A1U7WF58;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=E3 ubiquitin-protein ligase FANCL isoform X1 {ECO:0000313|RefSeq:XP_009773284.1};
GN Name=LOC104223525 {ECO:0000313|RefSeq:XP_009773284.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009773284.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009773284.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009773284.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_009773284.1; XM_009774982.1.
DR AlphaFoldDB; A0A1U7WF58; -.
DR SMR; A0A1U7WF58; -.
DR STRING; 4096.A0A1U7WF58; -.
DR GeneID; 104223525; -.
DR KEGG; nsy:104223525; -.
DR eggNOG; KOG3268; Eukaryota.
DR OrthoDB; 11501at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR Gene3D; 3.10.110.20; RWD domain-like; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR026848; Fancl.
DR InterPro; IPR026850; FANCL_C.
DR InterPro; IPR043898; FANCL_d2.
DR InterPro; IPR044037; FANCL_d3.
DR InterPro; IPR043003; FANCL_d3_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13206:SF0; E3 UBIQUITIN-PROTEIN LIGASE FANCL; 1.
DR PANTHER; PTHR13206; UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN; 1.
DR Pfam; PF11793; FANCL_C; 1.
DR Pfam; PF18890; FANCL_d2; 1.
DR Pfam; PF18891; FANCL_d3; 1.
DR SMART; SM01197; FANCL_C; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT DOMAIN 17..105
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18890"
FT DOMAIN 107..201
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18891"
FT DOMAIN 212..287
FT /note="FANCL C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11793"
SQ SEQUENCE 291 AA; 33724 MW; B92EF79831878AD0 CRC64;
MEYVDQNRCR ELAKSSSFYR RIYSEVEEIG WEHLVKLGED LRLLSFRMMD KKGRMHIVQI
TLDGTYPNHP PSISADMPYL FNVEWSINSR LKDVIRQFQQ HMDKLQEFWN IMDDIDHSLL
VSDLRYPQRA SSHRQLNIGN DCYIMFFIDA NDPTSLPDCR FLGSDSEVER LRAMWRRNCK
RWMKDKPFSE NLANVLDVQL HGPSSVEKTD PQTECGICYA QYLPIDDELG AKSGSGTDCT
CENNSCSRAF HSVCLGDWLS SITTTRQSFD VLFGNCPYCS DPIAVKINTR K
//
