ID A0A1U7WHH1_NICSY Unreviewed; 488 AA.
AC A0A1U7WHH1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Probable 26S proteasome non-ATPase regulatory subunit 3 isoform X2 {ECO:0000313|RefSeq:XP_009773690.1};
GN Name=LOC104223867 {ECO:0000313|RefSeq:XP_009773690.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009773690.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009773690.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009773690.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the proteasome subunit S3 family.
CC {ECO:0000256|ARBA:ARBA00007912}.
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DR RefSeq; XP_009773690.1; XM_009775388.1.
DR AlphaFoldDB; A0A1U7WHH1; -.
DR SMR; A0A1U7WHH1; -.
DR GeneID; 104223867; -.
DR OrthoDB; 514836at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR GO; GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR013586; 26S_Psome_reg_C.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10758:SF10; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3-RELATED; 1.
DR PANTHER; PTHR10758; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF08375; Rpn3_C; 1.
DR SMART; SM00753; PAM; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteasome {ECO:0000313|RefSeq:XP_009773690.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..445
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
SQ SEQUENCE 488 AA; 55440 MW; E43EC25ACF9CDB24 CRC64;
MEFLAFISVF YLAMVVVLIS QVFFKTNRTV KIEDQSAPSV YDCSVDPSVL QDLKEIASLI
ESGANTSEVR KIYKAMRLTM KLRRKLKVSI LSAFLNYALG PVSEVHAQLS SYLPQQDKYD
TQVDVEMPAT EAHSKHLVPE LEIYCYLLVL IFLIDQKKYN EAKACSSKSI VSLKNMNNRT
ADVLASKLYF YYSLSYEFAG DFAEIRGNLL ALYQIATVRH NKLSQETLIN LLLRNYLHYN
LYDQAEKFRS KAHCVDALSN QQLCRYLLYQ GKIKTIQLDY TDAKDSLLQA VQKSPVTAVG
FQIQCNKWAI IVQLLLGEIP ERTVFTQKRM EKSLRPYFEL TNAVRVGDLE LLRTVAVKFS
STFSQDRTSN LIVRLRHNVI RTGLRNISTA YSRISLADIA KKLNLDSEHP VDDAENLVAK
AIRDGAIDAT IDHANRWLVS KATGDVYSTN EPQIAFNSRI AFCLNMHNEA VHALRFPQNL
SNKQSVAT
//
