ID   A0A1U7WKV1_NICSY        Unreviewed;       613 AA.
AC   A0A1U7WKV1;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Glucosidase 2 subunit beta {ECO:0000256|ARBA:ARBA00022387};
GN   Name=LOC104229630 {ECO:0000313|RefSeq:XP_009780592.1};
OS   Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009780592.1};
RN   [1] {ECO:0000313|Proteomes:UP000189701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA   Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA   Peitsch M.C., Ivanov N.V.;
RT   "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT   tomentosiformis.";
RL   Genome Biol. 14:R60.1-R60.17(2013).
RN   [2] {ECO:0000313|RefSeq:XP_009780592.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaf {ECO:0000313|RefSeq:XP_009780592.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_009780592.1; XM_009782290.1.
DR   AlphaFoldDB; A0A1U7WKV1; -.
DR   GeneID; 104229630; -.
DR   OrthoDB; 103990at2759; -.
DR   Proteomes; UP000189701; Unplaced.
DR   CDD; cd00112; LDLa; 1.
DR   Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR   Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 1.
DR   InterPro; IPR039794; Gtb1-like.
DR   InterPro; IPR036055; LDL_receptor-like_sf.
DR   InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR   InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR   InterPro; IPR044865; MRH_dom.
DR   InterPro; IPR036607; PRKCSH.
DR   InterPro; IPR028146; PRKCSH_N.
DR   PANTHER; PTHR12630:SF1; GLUCOSIDASE 2 SUBUNIT BETA; 1.
DR   PANTHER; PTHR12630; N-LINKED OLIGOSACCHARIDE PROCESSING; 1.
DR   Pfam; PF12999; PRKCSH-like; 1.
DR   Pfam; PF13015; PRKCSH_1; 1.
DR   SUPFAM; SSF57424; LDL receptor-like module; 1.
DR   SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 1.
DR   PROSITE; PS51914; MRH; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..613
FT                   /note="Glucosidase 2 subunit beta"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010550194"
FT   DOMAIN          494..589
FT                   /note="MRH"
FT                   /evidence="ECO:0000259|PROSITE:PS51914"
FT   REGION          200..418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..280
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..322
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..393
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..411
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   613 AA;  69778 MW;  660242F0CF31AC6A CRC64;
     MMKIKFQFIF LISFIISSID RSVSLPSIDN LGISPQDENY YKGLSLGAIK CKDVSKKFTK
     SQLNDDFCDC PDGSDEPGTS ACSSGKFYCK NTGHIPLFIY SSRVNDGICD CCDGSDEYDG
     KVKCPNTCWE VGKVARDKLK KKIATYQEGI TLRRKEVEEA KLAITKEEAE LSKLKTEEKI
     LKDTVEQLKD KKEQIEKAEE KERLKREKEE KDRKEADDAN LEASKAEEKT EGQEEAVKSD
     IHDKIGLLED SPSIKDAVEG HDKNVDEVQH GDHSVNDEFP VDELEQVPED SSQHPEMKEE
     PSTNNDNVDE KDATENTESL SKEELGRVVG SRWLGKKSEQ ELEGVGAGSD TNHDNHNEVL
     PDTHEEEYNG YDSEEDEQKY DDGDSEDQVE DFVGEDHDSS SSHKSESDDD SDFADITTTS
     SPSWMEKIQQ TVKSIFRAVN LFQTPVNISD ADRIRKEYDE SSSKLTNIQS RISSLTEKLK
     QDFGPEKEFY SFHGQCFESK ENKYTYKICP FKEASQVEGY STTRLGNWDR FEDSYKTMQF
     SNGDHCWNGP NRSLKVKLRC GLKNELTDID EPSRCEYLAF LSTPALCREE KLKELQDKLE
     TMNREQPHGH DEL
//