ID A0A1U7WQV0_NICSY Unreviewed; 1097 AA.
AC A0A1U7WQV0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC104229927 {ECO:0000313|RefSeq:XP_009780958.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009780958.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009780958.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009780958.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_009780958.1; XM_009782656.1.
DR AlphaFoldDB; A0A1U7WQV0; -.
DR SMR; A0A1U7WQV0; -.
DR GeneID; 104229927; -.
DR KEGG; nsy:104229927; -.
DR eggNOG; ENOG502QPT1; Eukaryota.
DR OrthoDB; 460883at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF595; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 11.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|RefSeq:XP_009780958.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_009780958.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000313|RefSeq:XP_009780958.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 744..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 811..1093
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1097 AA; 121152 MW; 72854C07C2ACBB1F CRC64;
MSRVFDSRNG LILIWMVFLL ASVMLVYPIE GLNAEGIYLL ELKKNIIDKF NYLENWNSSD
ETPCKWKGVN CTSDYNPVVQ ILDLRSMNLS GSLSSSIGGL VCLTVLDLSY NEFTGNIPKE
IGNCSKLQSL QLNDNDFYGQ IPAELYNLSY LEELNLFNNM ISGPISEEFG KLSSLVSFVA
YTNNIIGPLP RSLGNLKTMI TFRVGQNLLS GSLPAEIGDC LNLQVLGLAQ NNIGGNIPKE
LGMLSSLKQL VLWDNQLSGY IPKELGNCTR LELFALYQNN LVGEIPVEIG KLKFLKRLYL
YRNGLSGTIP RVIGNLSSAL EIDFSENYII GEIPTEFSQI KGLKLLYLFK NQLKGAIPQE
LTSLRKLEHL DLSINYLTGP IPFAFQYLTE LVQLQLFQNS LSGSIPQHLG IYGRLWVVDL
SNNYLTGTIP PNICRNSDLI LLNLGSNNLH GDIPPSVINC VSLVQLRLNG NWLQGKFPSD
VCKLRNLSAL ELGQNTFGGL IPPEIGNCQN LQRLDLSGNY FTHELPNEIG NLQKLVTFNV
SSNLLTGQVP PKILKCKALQ RLDLSKNSFC GTVPDEIGKL AQLERLLVSE NKFYGKIPAA
LGRLSRLTEL QMGGNSYSGE IPPELGNLTG LQIAMNLSYN NLSGTIPPKL GNLILLEYLY
LNNNHLTGEI PITFQYLTGL MGCNFSYNNL TGPLPDIPLF QNMDVSSFIG NKGLCGGLLG
ECNESPSLNS DPVVESAGAP RGNIVTIIVA TVVGGVSLVL ILGVLYLMRR NPVQMVESIK
DMDASFPGSG IYFPPEEEFT FQDLVDATNN FHDSYIVGRG AVGTVYKAVM QSGKTIAVKK
LASNRECNNI EKSFRAEITT LGKIRHRNIV KLYGFCYHQG SNLLLYEYMA KGSLGELLHS
TSCSLEWPIR FKIALGAAEG LSYLHHDCKP QIIHRDIKSN NILLDEKLEA HVGDFGLAKV
VDVPQNKSMS AIAGSYGYIA PEYAYTMKVT EKSDIYSYGV VLLELLTGKT PVQPLDEGGD
LVTWVRHYIR DHSLTPGILD SRLDLTDKTT VNHMLTVLKI ALVCTSMSPV DRPSMREVVL
MLIESDEQEG NFILSQV
//
