ID A0A1U7WW46_NICSY Unreviewed; 662 AA.
AC A0A1U7WW46;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU366043};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU366043};
GN Name=LOC104228190 {ECO:0000313|RefSeq:XP_009778904.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009778904.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009778904.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009778904.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU366043}; Single-
CC pass type II membrane protein {ECO:0000256|RuleBase:RU366043}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361, ECO:0000256|RuleBase:RU366043}.
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DR RefSeq; XP_009778904.1; XM_009780602.1.
DR AlphaFoldDB; A0A1U7WW46; -.
DR STRING; 4096.A0A1U7WW46; -.
DR GeneID; 104228190; -.
DR KEGG; nsy:104228190; -.
DR eggNOG; ENOG502SKYN; Eukaryota.
DR OrthoDB; 1202783at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004159; Put_SAM_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10108:SF1144; METHYLTRANSFERASE PMT10-RELATED; 1.
DR PANTHER; PTHR10108; SAM-DEPENDENT METHYLTRANSFERASE; 1.
DR Pfam; PF03141; Methyltransf_29; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 2.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|RuleBase:RU366043};
KW Membrane {ECO:0000256|RuleBase:RU366043};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU366043};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Signal-anchor {ECO:0000256|RuleBase:RU366043};
KW Transferase {ECO:0000256|RuleBase:RU366043};
KW Transmembrane {ECO:0000256|RuleBase:RU366043};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366043}.
FT TRANSMEM 23..41
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366043"
SQ SEQUENCE 662 AA; 74835 MW; 2D9A9722E418A144 CRC64;
MKGLISSLSF SDHPHVSLTK TPTFLKIIVL SFLSIFLFFI VRRFSFDITT FITTPSSHEF
PMSFTSIPNQ TTTSTVAANP PPPPLRRPGM AVERTGIIDE NGAMTNDFVV GEFDEELIDS
VVNGKVNGTD EALESDENRG GLRGKIGKFK VCDESMRDYI PCLDNVEEIS RVNLSERGGN
LVSHCPPKGK GLDCLIPRPK DYKLRIPWPK SRDEIWLSNV PHTPFKEKAG NKWVKKKGDK
CIFPGDGTQF VLGANQYLDQ ISKMVPEIAF GQRTRVAMDI GGGVASFGAY LMDRNVSTLS
IATKDMHKNQ IQFALERGVP AMLTAFATHR LLYPSQAFDL IHCSRCSINW TRDDGILLLE
VNRMLRAGGY FIWKAEPIYR HDENLFAPLK EMENITRRLC WELLKNEGDI SIWRKPLNNS
CYLSRPLAVQ PSLCGVGDDP DNVWNVNLKT CITQLPENGY GANVTTWPAR LHSPPDRLFS
IKMDAELSRR EIYKAESKFW HEIISGYVGA FHWKELNLRN VMDMRALYGG FAAALHDLNI
DCWVMNVVPV SGSNTLPVLY DRGLIGVMHD WCEPFDTYPR TYDLLHAAAL FSVERNRCNV
TNIMLEMDRI LRPGGRVYIR DTTPVIEELE EIAHALGWVA FKFDGSEGPH SNWKLLIGEK
RL
//
