ID A0A1U7X618_NICSY Unreviewed; 553 AA.
AC A0A1U7X618;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Germacrene C synthase-like {ECO:0000313|RefSeq:XP_009785126.1};
GN Name=LOC104233427 {ECO:0000313|RefSeq:XP_009785126.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009785126.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009785126.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009785126.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004721}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR RefSeq; XP_009785126.1; XM_009786824.1.
DR AlphaFoldDB; A0A1U7X618; -.
DR STRING; 4096.A0A1U7X618; -.
DR GeneID; 104233427; -.
DR KEGG; nsy:104233427; -.
DR eggNOG; ENOG502QUCN; Eukaryota.
DR OrthoDB; 770856at2759; -.
DR UniPathway; UPA00213; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
DR GO; GO:0016102; P:diterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00684; Terpene_cyclase_plant_C1; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR Gene3D; 1.50.10.130; Terpene synthase, N-terminal domain; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR034741; Terpene_cyclase-like_1_C.
DR InterPro; IPR044814; Terpene_cyclase_plant_C1.
DR InterPro; IPR001906; Terpene_synth_N.
DR InterPro; IPR036965; Terpene_synth_N_sf.
DR InterPro; IPR005630; Terpene_synthase_metal-bd.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR31225:SF176; GERMACRENE C SYNTHASE-LIKE; 1.
DR PANTHER; PTHR31225; OS04G0344100 PROTEIN-RELATED; 1.
DR Pfam; PF01397; Terpene_synth; 1.
DR Pfam; PF03936; Terpene_synth_C; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01019; Terpene_Cyclase_Like_1_C_Termi; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT DOMAIN 25..201
FT /note="Terpene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01397"
FT DOMAIN 259..498
FT /note="Terpene synthase metal-binding"
FT /evidence="ECO:0000259|Pfam:PF03936"
SQ SEQUENCE 553 AA; 63904 MW; 1485213F635AC677 CRC64;
MSQVAFISTT TTDSGRPLAN FHSSVWGDYF LSYTPQLTEI SSQEKVEFEE LKEKVRQMLV
ETPDNSTQKL ELIDTNQRLG VAYHFGNEIQ TSITNIFDLF QQSENEDDDL YVAALRFRLL
RQQRHFISSD AFKKFTNKDG RFKETLTKNV QGLLSLYEAA HLRVHGEEIL EQALSFTLTN
LESMGPKLSN TSLKAQVSAA LSQPIYTNLP RLGAKKYMCM YEKNESHNDL LLKFAKLDFN
IVQKVYQREL YELTRYWWKD LDYANNFPYA RDRLVECYYG AVGVLFEPQY SRTRKILGKL
INVITMVDDT FDAYATFDEI VAFTNAIERC DISVMDSISP NLRPAYQVLI DFFNEMEKEL
AKEGKADRVY YAKFEMKKCI RAYFKEAQWL NVGYIPKCDE YLENGSASIG IMLMAVTSLV
GLEELITKET LEWVINDPLI LRVSGVISRL KDDIIGHNFE QQRGHVASFI ECYMKEHGVS
KQEAYAAVDK EMANAWKDIN TEFFRPSQVP TFVLERIINP TRLVIGFQEN DFINTQGEYK
DKITSLLVDS MKI
//
