ID A0A1U7XCT6_NICSY Unreviewed; 493 AA.
AC A0A1U7XCT6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cytochrome P450 94C1-like {ECO:0000313|RefSeq:XP_009789882.1};
GN Name=LOC104237426 {ECO:0000313|RefSeq:XP_009789882.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009789882.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009789882.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009789882.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
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DR RefSeq; XP_009789882.1; XM_009791580.1.
DR AlphaFoldDB; A0A1U7XCT6; -.
DR STRING; 4096.A0A1U7XCT6; -.
DR GeneID; 104237426; -.
DR KEGG; nsy:104237426; -.
DR eggNOG; KOG0157; Eukaryota.
DR OrthoDB; 3217781at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11064; CYP86A; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24296; CYTOCHROME P450; 1.
DR PANTHER; PTHR24296:SF30; OS05G0445100 PROTEIN; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 493 AA; 56992 MW; 8032ED30B14370F7 CRC64;
MDLETCWWLK SFHAYSILIF IIFSLFSLFF YIVKLKLWCN CEICHAYVTT SWSSQFTNLC
DWYTHLLQNS PTRTIHIHVL GNTITANPEN VEYMLKARFD NYPKGKTFST ILGDFLGRGI
FNVDGDLWRF QRRMSSLELG KVSIRSYAFE VVHTEIQKRL LPLLANKEGA VLDFQDVFRR
FSFDNICRFS FGLDPKCLES SLPISEFAIS FDLASKLSAE RAMTTSPIAW KIKRFLNIGS
ERKLKKAIKL INILAQEVIR QKRKLGFSNH RDLLSRFMGT ISDETYLRDI VISFLLAGRD
TIASALTSFF YVIANNPKVA KSIRDEVDRV LGPNKDLTCC EQMNELHYLQ ASIYESMRLY
PPIQFDSKFC LEDDILPDGT FVKKGTRVTY HPYAMGRMEE LWGCDSLEFK PERWLKDGIF
FQENPFKYPV FQAGLRVCLG KEMALVEIKS VALSLLRRFN VELAQPYHMP RFSPGLTASF
RGGLMVSVRE ISP
//
