ID A0A1U7XFF4_NICSY Unreviewed; 437 AA.
AC A0A1U7XFF4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Protein TRANSPARENT TESTA 12-like isoform X2 {ECO:0000313|RefSeq:XP_009789598.1};
GN Name=LOC104237189 {ECO:0000313|RefSeq:XP_009789598.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009789598.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009789598.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009789598.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR RefSeq; XP_009789598.1; XM_009791296.1.
DR AlphaFoldDB; A0A1U7XFF4; -.
DR GeneID; 104237189; -.
DR OrthoDB; 10858at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR CDD; cd13132; MATE_eukaryotic; 1.
DR CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR InterPro; IPR045069; MATE_euk.
DR InterPro; IPR002528; MATE_fam.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR11206:SF194; PROTEIN DETOXIFICATION; 1.
DR Pfam; PF01554; MatE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 134..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 437 AA; 49544 MW; 852724CE98A5E956 CRC64;
MGSVKDNEEN RQPLLAEATS ADWLLSKNTV ERVDEDDDKD LKTRVWIETK KLWHIVGPSI
FSRIASYTMN IITQGFAGHL GEVELAAISI SNTVIVGLNF GLLLGMASAL ETLCGQAFGA
KKHHMLGIYM QRSWIVLFLC CFLLLPLYIF ATPILRALGQ PDDVAELSGV VALWFIPLHF
SFAFQFPIQR FLQSQLKTAV LAWVSLAVLA IHTVVSWLFV YKLNLGIVGA AVALDISWWL
LFIGLFWYTA CGGCPETWSS FSTQAFSGLW EFIRLSAASG VMLCLENWYY RILMLMTGYL
ENATLALDAL SICDYAGDQD DRRSTSGYVF MLAVWLRRIL EELKFKQEKT TTIFCDNNSA
IKLSKNPVLR GRSKHIDVKY YFLRDLNNEG IIELTYCRSE DQLADIFTKP LKLLSFQNLR
RMLGLSTMEE LKKLKIN
//
