ID A0A1U7XNV6_NICSY Unreviewed; 589 AA.
AC A0A1U7XNV6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=LRR receptor-like serine/threonine-protein kinase FEI 2 {ECO:0000313|RefSeq:XP_009793727.1};
GN Name=LOC104240563 {ECO:0000313|RefSeq:XP_009793727.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009793727.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009793727.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009793727.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_009793727.1; XM_009795425.1.
DR AlphaFoldDB; A0A1U7XNV6; -.
DR GeneID; 104240563; -.
DR KEGG; nsy:104240563; -.
DR eggNOG; ENOG502QQCK; Eukaryota.
DR OrthoDB; 341734at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48056; LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED; 1.
DR PANTHER; PTHR48056:SF13; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_009793727.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Receptor {ECO:0000313|RefSeq:XP_009793727.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..589
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010553764"
FT TRANSMEM 237..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..576
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 336
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 589 AA; 64421 MW; F27DCFE3606E5089 CRC64;
MGGFSLKIRE LLFSSVLLLC IFSRVALALS PDGQALVNFR ISVLGSDGVL KQWRPEDSDP
CGWKGVLCDP KSKRVISLIL PDHKLSGSIS PDIGKLDQLQ FLALHDNNFY GTIPPALGNC
TKLKSLFLQG NYLSGWIPDE LGNLPELENL DLSSNSLSGN IPPSLGKLNN LVSFNVSTNF
LVGQIPTDGH LANFGNDSFL GNRNLCGQQI SQDCKAGGPS FSRSPVAAQN QSKNGRLLIS
ASATVGALLL VALMCFWGCF LYKRLGKNDG KSLAMDVCAG ASIVMFHGDL PYSSKDIIKK
LETLNGEHII GSGGFGTVYK LAMDDGNVFA LKRIIKMNEG FDRFFERELE ILGSIKHRYL
VNLRGYCNSP TSKLLIYDFL SGGSLDEVLH ERSEQLDWGA RLTVIMGAAK GLAYLHHDCS
PRVIHRDIKA SNILLDGNFE ARVSDFGLAK LLGDEESHIT TIVAGTFGYL APEYMQSGRA
TEKTDVYSFG VLVLEVISGK RPTDASYIEK GFNIVGWLNF LASENRRMEI VDPHCERVQT
ESLDALLSVA TQCVSSSPDD RPTMHRVVQI LESEVMTPCP SDFYDSNSD
//
