ID A0A1U7XZZ3_NICSY Unreviewed; 1196 AA.
AC A0A1U7XZZ3;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Myosin-2-like isoform X2 {ECO:0000313|RefSeq:XP_009792549.1};
GN Name=LOC104239582 {ECO:0000313|RefSeq:XP_009792549.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009792549.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009792549.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009792549.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR RefSeq; XP_009792549.1; XM_009794247.1.
DR AlphaFoldDB; A0A1U7XZZ3; -.
DR GeneID; 104239582; -.
DR OrthoDB; 5489458at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030048; P:actin filament-based movement; IEA:UniProt.
DR CDD; cd01383; MYSc_Myo8; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036022; MYSc_Myo8.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF769; MYOSIN-2-LIKE ISOFORM X1; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT DOMAIN 152..201
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 205..864
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..766
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1049..1082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 943..1030
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 15..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 296..303
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1196 AA; 136115 MW; 662E3AAE7A00A5A1 CRC64;
MLSVSAPSRT RSSLEEMLES LKQRDENEKP KDIPPALPTR PKSASRTRPP SPKRTLPNNT
TGNRGVVELE NGKKEEVKGK RGNMFGAKKG KEMIMEFSES PYVNSFSVEK EYRQRFWEKD
GAKLLDNNNR VHYSLPKFRE DEWNDNISYF IEKKLCVWCH LKNRQWEAGQ IQSTSGDKAS
VLLSDGSVVA VPIGELLPAN PDILQGVDNL IQLCYLNEPS VVHNLEHRYH QDRIYTKAGP
VLIAVNPFKE IQLYGNEHIT AYRQKLLDDP HIYSVADAAY SQMMEDEINQ SIIISGESGS
GKTETAKYAI EYLAMISGGN NRIESEVLQT SCILEAFGNA KTPWNNNSTR FGKLIEICFS
AEGGICGANV QTFLLEKSRV VQLAHGERSY HIFYQLCAGA PSALRDKLKL KGASDYNFLN
QSDYLVIHDV DDAKKFHMLV KALNTMGISE RDQEHAFQMV AVVLWLGNIT FQAIGSENNV
EVAQNEAVIN AASLLGCSAN DLMLALSTRR MQPGKDKVVK SLTMQQAIDT RDALAKFIYA
NLFDWIVDKI NKSLAMSKEK TARTINIVDI YGFESFEKNS FEQLCINYAN ERLQQHFDRH
LFKLEQEEYE LDGIDWTKVD FQDNQECLDL FEKKSIGLIS LLDEESNFHK ATDLTFTNKL
KQHLKANPCY KGDREEFGIR HYAGEVIYDT SGFLEKNRDT VHSDIIQLLS SSSEHLPKSF
ASSFANQSAD FQKQTVATKF KDLLFKLMQQ LESTAPHFVC CIKPNSKQVP GMYNNDLVFE
QLRCSGLLDI VRISRSGYPT RMTHQEFSKR YGVLLPQVHE SKDPLSMSVA ILRQFDILPE
MYQVGYTKLY FRAGQIAALE DVRKQVLQGT LEVPKCYSGH CARRHFHELE GGVIILQSFV
RGEIARRQYN ASLESKRKAA NKENDKQLVA VVQIQSAIRC WLAQRHLNQL QSLKKLNQDR
EKQGRKTSEV KDLPAEILPS VVEDLERRVM VAEASLDEKD KENAALKEQV NQLEARWSDY
EVRMRSMEEM WQKQMVSLQA SLAAAKKSLG VDNPAGHPGK REGSQSPCGY DSEDTTTMGT
HTPGGSTPIE FASNGVDFGG IRENNGGLCV VNYLNREFEL RRQNFDDEAM AIAQLKSEQL
HSTNPAEDFR RLRHRFEEWK KDYKARLKET KAKVHKFGYS EAEKTRRNWW GKKSKR
//
