ID A0A1U7YBN5_NICSY Unreviewed; 916 AA.
AC A0A1U7YBN5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Late blight resistance protein homolog R1A-10 isoform X1 {ECO:0000313|RefSeq:XP_009796664.1};
GN Name=LOC104243210 {ECO:0000313|RefSeq:XP_009796664.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009796664.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009796664.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009796664.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR RefSeq; XP_009796664.1; XM_009798362.1.
DR AlphaFoldDB; A0A1U7YBN5; -.
DR GeneID; 104243210; -.
DR KEGG; nsy:104243210; -.
DR eggNOG; KOG4658; Eukaryota.
DR OrthoDB; 5510284at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1193; DISEASE RESISTANCE PROTEIN RPP13-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT DOMAIN 172..393
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 916 AA; 105488 MW; 2F82615E669C3278 CRC64;
MADTDTDTGL NLLVENLLDS VREKAKFIAD NSKLQIYDLE DDFLHLEEQV QRLRALLNIA
AQWQINTSSK WKQLVNKDIR ITVHRAEDVI DGLALMFQLY LDKKQGLIVF DSIRGDSVRI
IRRDSVSNLA TKIDGLNEKV KEFLQNNQPA VQPEKNSQDL PLKENEVVGL KEEAEKVIKR
LVDGSEDLNV VPVVGMHGLG KTTLAIKVFN DPQILNQFDS RIWVYVGQSY EIKDIFINIL
TCFTDRIEEY QDKDVNEIAK VICDFVPKEG KCLIVLDDVW AIGVVDFVKK TFPENSKGHR
IMMTTHRQDV ASCANPNPHD LKFLTQTESF LLLKSRVFGS GCFPEELTEL GESIAQKCCG
VPLAIIVIAG ALRGRKDKNN WLKVQKYFWQ HLIIKDDPIR CWKFVEMSYN CLPQEMKECF
LYCGIFPRGF DIPAWKLIRL WIAEGLIKSS PGYALEEVAE NNLNELVNRN LVIVVQKKFD
SRIKTCRLHD MVQEFCKMEA TRECLFHEVS LTPDQAIPDD SRRLCIRSRF LGDFLSRKPY
AEHVRSFLCF SPTQLSPYLV TLLHKAFALI RVLDVEPTNF IFSRYFNGLY HLKYMAFSGD
FTAIPPPFCR FLNLQTLIFN TTSKRKRYLE TRWEIWNMLR LRHLHSNIPV RLPRPKTPKG
EISCLRTLSM VAPESCNSCV LAKVGNLKKL SIKGNMAPFL EINKDGFSNH GELKCLENLK
LLNDVFTMIS VLHLPPNFFR FARTLKKLTL SDTRFDWREA IGLEQLECLE VLKLKDAFTG
KSWKLEVGFS ELQALSIDTT DFETWEASTH HFPRLRHLVL IYCDKLEAVP ATFADIPSLR
EMRLENTSKA VRSAKEIERK KQEMQFLNNI EFKLTISFDV DYNEVEDLCG IVSPNIVIIT
IQFFPCMLAN SSSNFS
//
