ID A0A1U7YFA1_NICSY Unreviewed; 1171 AA.
AC A0A1U7YFA1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=LRR receptor-like serine/threonine-protein kinase FLS2 {ECO:0000313|RefSeq:XP_009801818.1};
GN Name=LOC104247488 {ECO:0000313|RefSeq:XP_009801818.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009801818.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009801818.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009801818.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR RefSeq; XP_009801818.1; XM_009803516.1.
DR AlphaFoldDB; A0A1U7YFA1; -.
DR STRING; 4096.A0A1U7YFA1; -.
DR GeneID; 104247488; -.
DR KEGG; nsy:104247488; -.
DR eggNOG; ENOG502QTTB; Eukaryota.
DR OrthoDB; 455055at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR47988:SF76; MDIS1-INTERACTING RECEPTOR LIKE KINASE 2-LIKE; 1.
DR PANTHER; PTHR47988; SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1; 1.
DR Pfam; PF00560; LRR_1; 13.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 16.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|RefSeq:XP_009801818.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_009801818.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_009801818.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1171
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010558511"
FT TRANSMEM 808..830
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 870..1166
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 1171 AA; 128906 MW; B00A2B0DCCA3C1BE CRC64;
MSKTVLYALA IFSFTFFIPL SYGQTPSLEI EVAALKAFKN SISDDPFGAL VDWTNANHHC
NWSGITCDPS SNHVINITLF ETQLKGEISP FLGNLSKLQV LDLTLNSFTG NIPPQLGHCT
ELVELILYEN LLSGEIPAEL GNLRNLQLID FGNNFLNGSI PDSICDCTEL LLVSLINNSF
TGKLPSDIGN LANLQLFVAY ENNFIGSIPT SIRKLTALQT LDLSENRLSG PIPPEIGNLS
SLETLQLHLN FLSGKIPSEL GLCTNLVTLN MYTNQFTGSI PPELGNLENL QTLRLYNNQL
NSSIPASLFH LKSLTHLGLS QNELTGQIPP ELGSSMSLQV LTLHSNRLSG EIPSTITKLT
NLTYLSLSFN LLTGSLPLEF GLLYNLKNLT ASNNLLEGSI PSSITNCSHL LVLTLTYNRI
TGEIPIGLGQ LSNLTFLSLG SNKMVGEIPD DFFNCSMLEV LDLSDNNFSG KLKPMIGRLS
KLRVLRARTN SFLGPIPPEI GKLSQLMDLV LDENSFSGVI PPDISMLSDL QGLSLYDNKL
EGKLPVQLFE LKQLNELRLQ NNNFLGPIPH QISKMELLSL LDLSGNKLNG TLPESMASLR
RLMTIDLSHN LLTGSLPRAV LASMRSMQFY LNVSSNFLNG TIPDEIGVLE MVQEIDMSNN
NLSGSIPRSF GRCKNLFSLD LSGNMLSGPA PGAILTKLSE LVFLNLSKNR LQSELPEMAG
LPHLRSVDLS HNKFKGIIPE RFASMPALKY LNLSFNQLEG HIPKGGVFNN IKLEDLLGNP
SLCGTKFLRP CSTKSIRTGT HGFSKKTLII LAALGSVFGL ILLVLGVFFL NQYMKKQKVK
DTEDMIPKYA SALSLKRFYQ KDLELATDNF SPENIIGASS LSTVYKGRLE DGKIVAVKKL
NHRFAAEADK CFDREVRTLS QLRHRNLVKV LGYAWESKKL KALVLEYMEK GNLDNIIYDQ
MVDDWTLSNR IDILVSVASG LSYLHSGYDF PIVHCDLKPS NILLDENMEA HVSDFGTARM
LGIHLQDGSS ISSASVFEGT IGYLAPEFAY MRKVTTKVDV FSFGVIVMEI ITKRRPTGLT
GADELPMTLH QIVRNAAANG INELIQIVDP NLASYVSKKQ DVVEGLLKLA LSCTSPDPED
RPDMEQVLSS LSKLRKMECM NSHACLVKDA I
//
