ID A0A1U7YG71_NICSY Unreviewed; 354 AA.
AC A0A1U7YG71;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Protein SRG1 isoform X1 {ECO:0000313|RefSeq:XP_009797810.1};
GN Name=LOC104244161 {ECO:0000313|RefSeq:XP_009797810.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009797810.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009797810.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009797810.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
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DR RefSeq; XP_009797810.1; XM_009799508.1.
DR AlphaFoldDB; A0A1U7YG71; -.
DR STRING; 4096.A0A1U7YG71; -.
DR GeneID; 104244161; -.
DR KEGG; nsy:104244161; -.
DR eggNOG; KOG0143; Eukaryota.
DR OrthoDB; 1057251at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IEA:UniProt.
DR GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009805; P:coumarin biosynthetic process; IEA:UniProt.
DR GO; GO:0002238; P:response to molecule of fungal origin; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47991; OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE; 1.
DR PANTHER; PTHR47991:SF221; PROTEIN SRG1-LIKE ISOFORM X1; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Vitamin C {ECO:0000256|ARBA:ARBA00022896}.
FT DOMAIN 207..307
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 354 AA; 40715 MW; 97678591E488A7F4 CRC64;
MAGLSPITAD IGCKLVQEIV KDGDEIPDKY VSKDFQYGAI DDDVLIMDIP LVDMKVLTSS
SACGREELGK LQSALCSWGC FQFQAINHGI EESLIDEVHK VSRQFFELSM EEKQKYARAA
DDIDGYGNDM VLYENQTLDW NDRIYLKVHP ENDRKLKYWP ENPKSFREIL EEYTSRSKLI
AEELLKSMAR CLNLPDDRFL KQYGDRPVIY ARFNFYPPCP RPKLVRGLKP HADGTAITIL
LHDKEVEGLQ VLKDNKWYRV PIMPYALLVI VGDQVEIMSN GLLKSPVHRA VTNSEKERIT
VAMFCSPESG IDIEPVEELI DDKRPRLYKT AKDYLATYFQ YYQQGKRPID AVKI
//
