ID A0A1U7YHE9_NICSY Unreviewed; 696 AA.
AC A0A1U7YHE9;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ferric reduction oxidase 4-like {ECO:0000313|RefSeq:XP_009798669.1};
GN Name=LOC104244859 {ECO:0000313|RefSeq:XP_009798669.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009798669.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009798669.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009798669.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_009798669.1; XM_009800367.1.
DR AlphaFoldDB; A0A1U7YHE9; -.
DR GeneID; 104244859; -.
DR KEGG; nsy:104244859; -.
DR eggNOG; KOG0039; Eukaryota.
DR OrthoDB; 2671609at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 2.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR PANTHER; PTHR11972:SF79; FERRIC REDUCTION OXIDASE 4-RELATED; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 308..411
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 696 AA; 78471 MW; F76F9639ACD7E754 CRC64;
MGSRFVWKIV LLLLFVGWLF IWIMLPTKTY KDSWTPQLQI KLNSTYFREQ GTNLLLFTFP
IMLIAALSCI YLHLYSKSSS DQSTNGNKGQ YFRSWKRPVL AMAPLGIVNA VELAFAAMFI
ALLIWSLANY VCISFGRLHM HNAGEKVWMA KFRSVFLRLG YIGNICYAFL FFPVTRLSSI
LPLVGLTSES SVKYHIWLGH ASMALAVLHS VGFVIYYAVS HQMIEMLEWS STYVSNMAGE
IAALVAIAMW CTSLYKIRRK MFEVFFYAHQ LYILYIFFYL LHVGAAYTCM ILPGIFLFVI
DRYLRFLQSK RRARLISARL LPCSTIELTF SKNPALTYNP TSILFVNVPS VSKLQWHPFT
VVSNSNLEED KLSVVIKCMG SWSQKLEKQL SCSPDHLQIS TEGPYGPSSS HFLSRECLVM
VSGGSGITPM ISIIRELIYR STQPNTKVPK VILISAFQNT ADLAMLDLLL PVSSTPADIS
NLDLQIEAYI TRENGQEHNA LSHQLIQTIV FKHNPNDSAI SAALGPSSWL WLGAIISSSF
VMFLLLLGIV TRYSIYPIER DGRLYHYSAK IIWDMFLVCA SIFIATSIIF MWQKRDNEAE
GKQIQNVDLP TPTGSPAGLL CGTARELESL PHQSLVQATK VHYGARPDLK RILFDCKASD
VGVVVCGPQS MRHEVAKICA SGLAENLHFE AISFNW
//
