ID A0A1U7YR22_NICSY Unreviewed; 948 AA.
AC A0A1U7YR22;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Transcription factor LHW-like isoform X2 {ECO:0000313|RefSeq:XP_009804416.1};
GN Name=LOC104249641 {ECO:0000313|RefSeq:XP_009804416.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009804416.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009804416.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009804416.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_009804416.1; XM_009806114.1.
DR AlphaFoldDB; A0A1U7YR22; -.
DR GeneID; 104249641; -.
DR OrthoDB; 347824at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd18915; bHLH_AtLHW_like; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR043561; LHW-like.
DR InterPro; IPR025610; MYC/MYB_N.
DR PANTHER; PTHR46196; TRANSCRIPTION FACTOR BHLH155-LIKE ISOFORM X1-RELATED; 1.
DR PANTHER; PTHR46196:SF12; TRANSCRIPTION FACTOR LHW-LIKE; 1.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 738..787
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 664..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 948 AA; 104177 MW; AADE8CC4F25ADCFA CRC64;
MGYLLKEVLK TLCGVNQWSY AVFWKIGCQN TKLLIWEESY CETSTFSGLH GTCEVENPKL
AFQDWSACWD SGEVQNSQLL NQAGESLCLL VKRMMMDKQF NLVGEGLIGR AAAIGNHQWI
LSKGQSKDAH PPEVLKELSQ QFSSGIQTIS VIPVLPHGVV QFGSYLHILE NMGFVEDVRT
LISQLGCVPG VLLSDENAMK EPAPSTARPV YPGSSVSMVS CGRAKVMTSS SIIASCNYSA
NSIQAERFIG QTSSLAGQIQ ACMQSSDSTF QASNITGRFA KYHDDHFHKK ISPEVTSYMS
TNSQLTNNVI KAEVIPPNPD VWTKQQASLH IPKPRFCQES SVGSLTLDSG SIRLTEQQIS
GENNLAKNNS TLPNGFRASQ PRIGDVLTSN FHENIVLPST GVTELYKEVN KYQKSMPSPN
VFLDAIRPPH KIISCTEFTG NGLQIGSSEL KASSSYDVVN DVINNRSLDG RGTQFLLDGS
KRMVENDLFQ ALGIMSTRDE QPSSSEYIQD VYGEKHEHGV QNPLFDNAKF EDVCVQSQSG
YDLFDVLGAD FKNRLLNGSW SDEQSKGPDS NTKDCINNCS TSKISRDASS TVNQGNSDSG
MFSMTGFDRI LETMVSNRTT KQSLEDNLSC RTTLTNLSSS SSPNASCFYG RVGFSSQIQG
ELYGPPKTLS KSGATSSDSF KYECSKENTG THSQSCSIYG SQTSSWVESG HGTKPLSSVS
TGYSKKPDEM SKTSRKRLKP GENPRPRPKD RQMIQDRVKE LREIVPNGAK CSIDALLERT
IKHMLFLQSV TKHADKLKQT GESKIISKEG GLLLKDNLEG GATWAYEVSS QSMVCPIVVE
DLNQPRQMLV EMLCEERGLF LEIADIIRGL GLTILKGVME TRNDKIWARF AVEAYRNVTR
MDIFISLVRL LESTAKGETE PANANDNNTA VVNLFHQAAS IPATGSLL
//
