ID A0A1U7YRD2_NICSY Unreviewed; 717 AA.
AC A0A1U7YRD2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Proline-rich receptor-like protein kinase PERK12 isoform X1 {ECO:0000313|RefSeq:XP_009804511.1};
GN Name=LOC104249730 {ECO:0000313|RefSeq:XP_009804511.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009804511.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009804511.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009804511.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_009804511.1; XM_009806209.1.
DR AlphaFoldDB; A0A1U7YRD2; -.
DR SMR; A0A1U7YRD2; -.
DR STRING; 4096.A0A1U7YRD2; -.
DR GeneID; 104249730; -.
DR KEGG; nsy:104249730; -.
DR eggNOG; KOG1187; Eukaryota.
DR OrthoDB; 451134at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR InterPro; IPR020635; Tyr_kinase_cat_dom.
DR PANTHER; PTHR47989; OS01G0750732 PROTEIN; 1.
DR PANTHER; PTHR47989:SF54; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00219; TyrKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_009804511.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Receptor {ECO:0000313|RefSeq:XP_009804511.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transferase {ECO:0000256|ARBA:ARBA00022777,
KW ECO:0000313|RefSeq:XP_009804511.1}.
FT DOMAIN 399..685
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 188..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 80804 MW; DF4E2CBBE25252BF CRC64;
MFPPKPERRT QSMPRGISPH LTDKVIVAVK AEKVITKTAL AWALTHVVRP GDCITLLAVF
AVEKTERRRF WGFPRMRGDC RSNGRTNSHD RIGQITETCS QMVLQFHDHI DVRVRIKVVS
ALSVGVVAAE AKNNAVSWVI LDKKLKLELK HCMEELRCNI VVMKGSKPKV LRLNLGCSEE
LQTPFFSANS SPVKDSREIQ DERMKHSTPV SSPEDQRTSY MRTPLLNSLT DPDTFLLYER
NPLYEGFSRE TFSPVHKQSV CDHVNDLHSF GERIITLSTV PKSQSHTHKT ILWIQQNHII
ADNNSAVENC KITSRSVTSG NKHENSIEYN QNLNTQGSKF NRDTDRDYLN SSIREAVSLG
RTSSIPLPLC SFCQCKAPSF GKPPKQFRYE ELEEATNGFS GTNFLAEGGF GLVHKGVLRD
GVVVAVKQLK FIGSQADADF RREVRVLSCA QHRNVVLLVG YCIQGNRRLL VYEFICNKSL
DFHLHGTKET ALDWSSRLKI AIGTARGLRY LHEDCRVGCI VHRDLRPKNI LLTHDFEPLV
ADFGLARLYN ECEASEDEHL IRTSRYLAPE YSNDGKVTEK VDVYAFGLVV LELITGRRTN
DLQCYRSQHL LAGSLSPTAG NGPYHLSAFK NQLLDSNLTS SPLENFPYEL QAMSHAAFMC
LQEDPQLRPP ISKVLKILEG GGAIFDSNSF GSRSGYMQGS NFNNHPVSKR HSRRLSY
//
