ID A0A1U7YV88_NICSY Unreviewed; 628 AA.
AC A0A1U7YV88;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=BTB/POZ domain-containing protein DOT3 isoform X1 {ECO:0000313|RefSeq:XP_009802685.1};
GN Name=LOC104248184 {ECO:0000313|RefSeq:XP_009802685.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009802685.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|RefSeq:XP_009802685.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009802685.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00982}.
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DR RefSeq; XP_009802685.1; XM_009804383.1.
DR AlphaFoldDB; A0A1U7YV88; -.
DR GeneID; 104248184; -.
DR KEGG; nsy:104248184; -.
DR eggNOG; ENOG502QR2D; Eukaryota.
DR OrthoDB; 2940143at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR043454; NPH3/RPT2-like.
DR InterPro; IPR027356; NPH3_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR32370:SF99; BTB_POZ DOMAIN-CONTAINING PROTEIN DOT3; 1.
DR PANTHER; PTHR32370; OS12G0117600 PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF03000; NPH3; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS51649; NPH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701}.
FT DOMAIN 56..125
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 213..510
FT /note="NPH3"
FT /evidence="ECO:0000259|PROSITE:PS51649"
FT REGION 602..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 545..579
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 602..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 72480 MW; CF86B29F4983207F CRC64;
MQKLIQLDQL ENTGDVSDDT RQLHDQRIVV PTILNQIADG FEKKEQSWFA TSQLPSDLSI
RVDDITFYVH KYPLVARCAY LREIEFQPQN SHLGYDLKLE KFPGGSENFE MILKFCYGLP
ISLNPGNVAA LRCGSEFLEM TEAMEEGNLI STTEAFFTFV VLSSWNDSIT VLKSCEMLSP
WAENLQIVRR CCDSIGWKIF RKNSTEEITN EGTWWFDDIA TLRINFFLRI ITAIRVKGIK
PEIIGSCIMH YGEKWLPNMN SETKGTDKYG NIRNDSQWSI TSGRMQEKSI GQNNKEQRII
IESLISILPP QKEAVSCKFL LRLLKMAMLY AASPALISEL EKRIGMVFEN AGLNDLLIPS
YAVSEQTINS TEEQTIYNID VVQRILDYFL LYEQQKLQQQ EMKSSTTVNI SKLVDSYLAE
IARDHNVSIT KFQVLAESLP RHIRTCHDGL YRAIDTYLKT HPSLSEHDRR RLCKIMDSEK
LSLDACMHAA QNERLPLRIV IQRILQVLLS EQVKMRAAVQ GKDIIASDDY NLDKENNWLS
TKKEVKSLKE ELEKVKIQMT GLQRDYSELQ QEYEKLNNKP RIPWTSGWRK IKKSALFNRK
MVEEETQEGE NRVKPGRRGS ISRRQSIS
//
