ID A0A1U7Z0H5_NICSY Unreviewed; 303 AA.
AC A0A1U7Z0H5;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Aquaporin NIP6-1 {ECO:0000313|EMBL:DAC84354.1, ECO:0000313|RefSeq:XP_009804420.1};
GN Name=LOC104249645 {ECO:0000313|RefSeq:XP_009804420.1};
OS Nicotiana sylvestris (Wood tobacco) (South American tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4096 {ECO:0000313|Proteomes:UP000189701, ECO:0000313|RefSeq:XP_009804420.1};
RN [1] {ECO:0000313|Proteomes:UP000189701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23773524; DOI=10.1186/gb-2013-14-6-r60;
RA Sierro N., Battey J.N., Ouadi S., Bovet L., Goepfert S., Bakaher N.,
RA Peitsch M.C., Ivanov N.V.;
RT "Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana
RT tomentosiformis.";
RL Genome Biol. 14:R60.1-R60.17(2013).
RN [2] {ECO:0000313|EMBL:DAC84354.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=32517797;
RA De Rosa A., Watson-Lazowski A., Evans J.R., Groszmann M.;
RT "Genome-wide identification and characterisation of Aquaporins in Nicotiana
RT tabacum and their relationships with other Solanaceae species.";
RL BMC Plant Biol. 20:0-266(2020).
RN [3] {ECO:0000313|RefSeq:XP_009804420.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_009804420.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
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DR EMBL; BK011459; DAC84354.1; -; mRNA.
DR RefSeq; XP_009804420.1; XM_009806118.1.
DR STRING; 4096.A0A1U7Z0H5; -.
DR GeneID; 104249645; -.
DR KEGG; nsy:104249645; -.
DR eggNOG; KOG0223; Eukaryota.
DR OrthoDB; 5490746at2759; -.
DR Proteomes; UP000189701; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR NCBIfam; TIGR00861; MIP; 1.
DR PANTHER; PTHR45724; AQUAPORIN NIP2-1; 1.
DR PANTHER; PTHR45724:SF19; AQUAPORIN NIP6-1; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 31193 MW; 489325A3A1C7A817 CRC64;
MDAEDGTSAP STPATPGTPG APLFGGFKHE RNSNGRNSLL KSLKCFSVEA WASEEGSLPP
VSCALPPPPV SLARKVGAEF IGTMILIFAG TATAIVNQKT QGSETLIGLA ASSGLAVMIV
ILSTGHISGA HLNPAVTIAF AALKHFPWKN VPVYIGAQII ASFCAAFTLK VVLHPIMGGG
VTVPSGSYLQ AFALEFIISF NLMFVITAVA TDTRAVGELA GIAVGATVML NILIAGETTG
ASMNPVRTLG PAVAAGNYKA IWIYLTAPIL GALAGAGIYS AVKLPNEDDN NHGKPSVEHS
FRR
//
