ID A0A1U7ZG31_NELNU Unreviewed; 997 AA.
AC A0A1U7ZG31;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC104589770 {ECO:0000313|RefSeq:XP_010246505.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010246505.1};
RN [1] {ECO:0000313|RefSeq:XP_010246505.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010246505.1; XM_010248203.2.
DR AlphaFoldDB; A0A1U7ZG31; -.
DR GeneID; 104589770; -.
DR OrthoDB; 991910at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF105; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|RefSeq:XP_010246505.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_010246505.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_010246505.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..997
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010582059"
FT TRANSMEM 579..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 640..900
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 965..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 977..991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 110663 MW; 8445BFD2A7539A20 CRC64;
MAVLADSSKI LSALLCFLVL NCFAGFRSEA RVLPDEEVQA LRKISAKLNN KYWTIKSTSC
SGGFINSYNY ARNIISNITC DCSYNAFTVC HITKFKMEGM NLTGILPDEF GDLPYLTEID
LIRNYINGTI PVSWTRIPLV TINLIGNRIS GSIPAEFGSV ETLEELVLED NQLGGTLPPQ
LGNLTRLRRL LLSANNITGP LPETFGKLKN LTDFRIDGNS ISGRIPNFIG NWTKINILNM
QGTSLEGPIP SEISFLTNLI QLRVSDLNGS NMSFPDLSGM KSITDLILRN CMITGQIPDY
ISEMKNIIRL YLTNNSLTGS VPSWIIDNKK YIDISYNNFT GYSPQPGCEQ TNVKTVASYS
SPEGNLVNWC LKKDLSCSSK PRYHSLFINC GGPKVVIHGE EYEEDLSPMS SSAFHASNER
WACSTTGDYL YSDPPNFKVQ ANTALNVTDS ELYSTARLSP LSLKYYGLCL RKGSYTVKLH
FAEIIYTEDR TFSSLGERIF DVLIQGEIRL KDFNIAKEAN GVGKSNIQEF KDVFVDGSTL
EIHLYWSGKG TTAIPDRGVY GPLISAITVT PNFNPDTGLS VGAIVGIVAA ACVVLILILV
TLRMNGYLGR KDLEDNELGG LEIQSGYFSL KQIKSATGNF DPENKIGEGG FGPVYKGILP
DGTVIAVKQL SSKSKQGSRE FLNEIGMISA LQHPNLVKLF GCCVEGNQLL LIYEYMENNS
LARALFGSEE HRLELNWPVR RKICLGIARG LAYLHEESRL KIVHRDIKAT NVLLDKDLNA
KISDFGLAKL DEEGNTHIST RIAGTIGYMA PEYAMRGYLT DKADVYSFGV VLLEIVSGKS
NTSYRPKEDF VYLLDWAYVL QEEDNLLELV DPTLESRYSK EEALRMLSLA LLCTGPSPFL
RPTMSSVVSM LEGKIPVQAP LNQSSMNDEL RLRAFEKFSQ DSQSYISGTS QESWVQKSIS
ADDPRFGSTT SFPYNEENEH QSDERKLIHD VNDISLN
//
