ID A0A1U7ZH29_NELNU Unreviewed; 220 AA.
AC A0A1U7ZH29;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363014};
DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU363014};
GN Name=LOC104590487 {ECO:0000313|RefSeq:XP_010247474.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010247474.1};
RN [1] {ECO:0000313|RefSeq:XP_010247474.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|RuleBase:RU363014};
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DR RefSeq; XP_010247474.1; XM_010249172.2.
DR AlphaFoldDB; A0A1U7ZH29; -.
DR GeneID; 104590487; -.
DR OrthoDB; 298369at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR000297; PPIase_PpiC.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR PANTHER; PTHR43629; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR PANTHER; PTHR43629:SF2; RHODANESE-LIKE_PPIC DOMAIN-CONTAINING PROTEIN 12, CHLOROPLASTIC; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF13616; Rotamase_3; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS50198; PPIC_PPIASE_2; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00278,
KW ECO:0000256|RuleBase:RU363014};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00278,
KW ECO:0000256|RuleBase:RU363014}.
FT DOMAIN 12..102
FT /note="PpiC"
FT /evidence="ECO:0000259|PROSITE:PS50198"
FT DOMAIN 126..218
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 220 AA; 24743 MW; 549937E4F6759B88 CRC64;
MVPSSRLERR GGREILVQHL LVSEDNQKLL PEFQERISGG TDLSELAAEH SICPSKENGG
ILGWVRKGQM VPEFEEAAFS APLNKVVQCK TKFGYHLFQV LSEKEELLLQ DIDPNDLYVK
MQDPIFFNEA QLIDVREPEE VAQASLPGFQ VLPLQQFGSW SPEITTKFDP SKDTYVLCHH
GVRSLQVANW LQTQGFKRVF NVSGGIHAYA VKADASIPTY
//
