ID A0A1U7ZH75_NELNU Unreviewed; 624 AA.
AC A0A1U7ZH75;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN Name=LOC104592955 {ECO:0000313|RefSeq:XP_010250838.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010250838.1};
RN [1] {ECO:0000313|RefSeq:XP_010250838.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC known as the alpha DNA polymerase-primase complex) which plays an
CC essential role in the initiation of DNA synthesis.
CC {ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
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DR RefSeq; XP_010250838.1; XM_010252536.2.
DR AlphaFoldDB; A0A1U7ZH75; -.
DR GeneID; 104592955; -.
DR OrthoDB; 49016at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.60; -; 2.
DR Gene3D; 1.10.8.530; DNA polymerase alpha-primase, subunit B, N-terminal domain; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR043034; DNA_pol_alpha_B_N_sf.
DR InterPro; IPR016722; DNA_pol_alpha_bsu.
DR PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703}.
FT DOMAIN 362..572
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 123..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 624 AA; 69436 MW; CA7FFABF8C59A2B9 CRC64;
MEEEIKAEFE RSGFSIDEED ILKKCLTFCI NCKLTPSDLV SSWEVYYLNR QLSGSLVQNA
QMDGFLLHLQ NEQKDAIIKE EPNLHIYSSN DVDMILCDEH EDTKEGILGT PTDRPENIYP
ESFDITPGTT GNRRPSSGKP SRLASNNMTP FGQRTSKFVV QSAFNNPLDE GNDVKEQEID
NTENDIIRRV QPIKRCSLQV CGSQPEPGCR FMYDRVEDRF NSLENRIRRH AIALVASGLY
EEPTDPTVAS QNKVFSVGMV CCDGEGRLNE KSVLLQGSVE HCGGQRVRLD LHKLTQFSLF
PGQVVGIEGH NPSGHCFVAS KVVDYMPLSI SPNADLAPAK KQHLDEEFNP PPSNMLEELS
LIIAAGPFTT TDNLFFEPLS ELLAYATRKQ PQLLMLLGPF VDSEHPDIKK AAIDRSFEEV
FHEEVLKRVQ DYAAFMGSAA RVVLVPSIRD AHHDFVFPQP PLDIHFSDLK HQITSFANPG
LFDANKVKIG CCSMDILRQL SGEEISRNPA NGLSGDRMGR LACHLVNQRS FYPLYPPAEG
VPLDLSLVPE ALQIPSVPDI LVLPSDLAPF VKVLPFGQRM NEEEQVKCIC INPGRLAKGV
GGGTFVELNY HGNADRTSAS VIRI
//
