ID A0A1U7ZHJ4_NELNU Unreviewed; 380 AA.
AC A0A1U7ZHJ4;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Nuclear transcription factor Y subunit {ECO:0000256|RuleBase:RU367155};
GN Name=LOC104590654 {ECO:0000313|RefSeq:XP_010247679.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010247679.1};
RN [1] {ECO:0000313|RefSeq:XP_010247679.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes.
CC {ECO:0000256|RuleBase:RU367155}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding.
CC {ECO:0000256|ARBA:ARBA00025911}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367155}.
CC -!- SIMILARITY: Belongs to the NFYA/HAP2 subunit family.
CC {ECO:0000256|RuleBase:RU367155}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010247679.1; XM_010249377.2.
DR AlphaFoldDB; A0A1U7ZHJ4; -.
DR STRING; 4432.A0A1U7ZHJ4; -.
DR GeneID; 104590654; -.
DR KEGG; nnu:104590654; -.
DR eggNOG; KOG1561; Eukaryota.
DR InParanoid; A0A1U7ZHJ4; -.
DR OrthoDB; 1119073at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 6.10.250.2430; -; 1.
DR InterPro; IPR018362; CCAAT-binding_factor_CS.
DR InterPro; IPR001289; NFYA.
DR PANTHER; PTHR12632:SF84; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT A-2; 1.
DR PANTHER; PTHR12632; TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED; 1.
DR Pfam; PF02045; CBFB_NFYA; 1.
DR PRINTS; PR00616; CCAATSUBUNTB.
DR SMART; SM00521; CBF; 1.
DR PROSITE; PS00686; NFYA_HAP2_1; 1.
DR PROSITE; PS51152; NFYA_HAP2_2; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU367155};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367155};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367155};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU367155}.
FT REGION 107..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 41713 MW; 4AEAD51D5F92A5CF CRC64;
MWVFSYGGAD VEAVDDLVSY QSLWLPTTDV IRLKQESNFT LQDNSSDFLS RKFRMQTLCF
KEHGGIAHNS ASQLSPFASV PWWSSLGSQP PYGESFGQLK SFSLDNPSGG NQLTAAPPQA
QLGTDHGQGK DSYSTAHFTI FPGDSRDSGK GSKPQQIPST IARQSFPPDY QVRVELGLGQ
PMACANYPYM DQCYGIFTTY GSQTVMNQGR VMLPLNMTED GPIYVNAKQY HGIIRRRQSR
AKAEMENKLI KVRKPYLHES RHLHAMRRAR GCGGRFLNTK NTNSQKGTND TGKASNVQSS
GSPTSEVLQS ESANANTSRE ASVGAGLEVT SLYSRGNFDR FHIDRLHPSA FHSNIVDSGQ
GMGITSKWVA AADGCCDLKV
//
