ID   A0A1U7ZMC6_NELNU        Unreviewed;       863 AA.
AC   A0A1U7ZMC6;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=ribonuclease P {ECO:0000256|ARBA:ARBA00012179};
DE            EC=3.1.26.5 {ECO:0000256|ARBA:ARBA00012179};
GN   Name=LOC104592164 {ECO:0000313|RefSeq:XP_010249682.1};
OS   Nelumbo nucifera (Sacred lotus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX   NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010249682.1};
RN   [1] {ECO:0000313|RefSeq:XP_010249682.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00000928};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the PPR family. P subfamily.
CC       {ECO:0000256|ARBA:ARBA00007626}.
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DR   RefSeq; XP_010249682.1; XM_010251380.2.
DR   AlphaFoldDB; A0A1U7ZMC6; -.
DR   GeneID; 104592164; -.
DR   OrthoDB; 47419at2759; -.
DR   Proteomes; UP000189703; Unplaced.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11980; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR002885; Pentatricopeptide_rpt.
DR   InterPro; IPR033443; PPR_long.
DR   InterPro; IPR031595; PRORP_C.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR13547:SF7; RIBONUCLEASE P; 1.
DR   PANTHER; PTHR13547; UNCHARACTERIZED; 1.
DR   Pfam; PF17177; PPR_long; 2.
DR   Pfam; PF16953; PRORP; 1.
DR   PROSITE; PS51375; PPR; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          195..271
FT                   /note="Pentacotripeptide-repeat region of PRORP"
FT                   /evidence="ECO:0000259|Pfam:PF17177"
FT   DOMAIN          373..517
FT                   /note="Pentacotripeptide-repeat region of PRORP"
FT                   /evidence="ECO:0000259|Pfam:PF17177"
FT   REPEAT          430..464
FT                   /note="PPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT   DOMAIN          559..736
FT                   /note="PRORP"
FT                   /evidence="ECO:0000259|Pfam:PF16953"
FT   REGION          101..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..361
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          770..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..138
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   863 AA;  96809 MW;  3AB2CEFAB9E2531B CRC64;
     MASFPFESLQ PKELHSMALC KYPSTLISFK SHFCSNFFSV STRKQTFHQD FSSVFVVRAN
     VSNMDAKLSG RRHSHSSKTI SSIAQRQMGY GFKTLKSSDK RVERKSMKAT VSSVMEEKTE
     RRFGKSNYNR KDRVSRTKQE MGSQFSSFKP KDERRGEKYK ENKSNVLVDK KEAENSKQSK
     GTSQVGEEKT AGKSNKSEDD SSQIPLRVEL DMCSKRGDVL GAISLYDSAQ KDGIKLGLYH
     YTVLLYLCSS AAVGVIRPAK SGSGSRSFKK LNLISELSSA NSVVLNEIGE KGNGSFDSTK
     LSFDESGNSS GASSDKLASS SSEFLVGLVG GKATEPNSLF SDGFTMSNES ESDSVRERDN
     QQDCEIRVSG NVKKYALRRG FEIYEKMRLE NVPLNEAALT AVARMAMSMG NGDLAFEMVK
     QMKPLGINPR LRSYGPALFS FCSSGDIEKA FTVEEHMLKH GVYPEEPELE ALLRLSVNAG
     RSDKVYYLLH KLRTSVRQVS PPTADLIERW FKSKEASRIG RRKWDKKSIT DAIENGGGGW
     HGQGWLGKGK WTVNRTFVRD DGVCKGCEEK LTTIDLDPIE TENFAKSVAS IAAKRERNSS
     FQKFQKWLDY YGPFEAVVDA ANVGLFSQRK FSLSKVNAVV NGIRQILPSK KWPLIVVHNK
     RITGDRMDQP TNRTLIEKWK NADALYATPT GSNDDWYWLY AAIKFKCLIV TNDEMRDHIF
     QLLGNDFFPK WKERHHESEK GHWHIPIASE HDSTGERTWL CIKRAGMHMR KQGSSTRPKE
     ANTPRLSKGG AKVDVRTKSP VKLPTLDHCS DETFHGNSKL PPEEIYRNLR NILATSLSPN
     DNTILSQIEA AEKLGGCSID FQI
//