ID A0A1U7ZMF2_NELNU Unreviewed; 417 AA.
AC A0A1U7ZMF2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Equilibrative nucleotide transporter 8 {ECO:0000313|RefSeq:XP_010254429.1};
GN Name=LOC104595403 {ECO:0000313|RefSeq:XP_010254429.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010254429.1};
RN [1] {ECO:0000313|RefSeq:XP_010254429.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR RefSeq; XP_010254429.1; XM_010256127.2.
DR AlphaFoldDB; A0A1U7ZMF2; -.
DR STRING; 4432.A0A1U7ZMF2; -.
DR GeneID; 104595403; -.
DR KEGG; nnu:104595403; -.
DR eggNOG; KOG1479; Eukaryota.
DR InParanoid; A0A1U7ZMF2; -.
DR OrthoDB; 239997at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IBA:GO_Central.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF77; EQUILIBRATIVE NUCLEOTIDE TRANSPORTER 8; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 417 AA; 45902 MW; 439A0C6111D82794 CRC64;
MEGGKGLVVV AEPRDSYNIA YIIHFFLGAG NLIPWNALIT AVDYFGYLYP AKHIDRVFSV
AYMGSSLPVL VLMMSWGSWN KKPSFRLRMN LGFSMFVLSL MTAPVMDWAR WSRKAEHGAY
SVTVAAVAVC GLADGLVGGS LIGSAGELPK RYMQAVFAGT ASSGVLVSIL RIITKASLPK
TTQGLQVSAH LYFIVSTLIV LVCIVCSNIL ERLPIVQMYR NKKTVTPRSE APNFSDDLRS
TMSRLCAVNE PNGQPKFWDV ARKIRWSAFG ILIIYTVTLS IFPGYISENV ESKLFQDWYP
ILLITMYNIL DLVGKSLTAV YVPKRIGKVT WACVARLLFY PLFTACLHGP KWLRTEVPVV
SLTCMLGLTN GYLTSVLMIL TPKTVPVAEA EVAGVVMALF LGIGLVGGSV LGWFWII
//
