ID   A0A1U7ZN62_NELNU        Unreviewed;       304 AA.
AC   A0A1U7ZN62;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Bifunctional nuclease 2-like isoform X2 {ECO:0000313|RefSeq:XP_010254738.1};
GN   Name=LOC104595630 {ECO:0000313|RefSeq:XP_010254738.1};
OS   Nelumbo nucifera (Sacred lotus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX   NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010254738.1};
RN   [1] {ECO:0000313|RefSeq:XP_010254738.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Bifunctional nuclease with both RNase and DNase activities.
CC       Involved in basal defense response. Participates in abscisic acid-
CC       derived callose deposition following infection by a necrotrophic
CC       pathogen. {ECO:0000256|ARBA:ARBA00025428}.
CC   -!- SIMILARITY: Belongs to the bifunctional nuclease family.
CC       {ECO:0000256|ARBA:ARBA00009095}.
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DR   RefSeq; XP_010254738.1; XM_010256436.2.
DR   AlphaFoldDB; A0A1U7ZN62; -.
DR   GeneID; 104595630; -.
DR   OrthoDB; 304718at2759; -.
DR   Proteomes; UP000189703; Unplaced.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.690.10; Bifunctional nuclease domain; 1.
DR   InterPro; IPR036104; BFN_sf.
DR   InterPro; IPR003729; Bi_nuclease_dom.
DR   PANTHER; PTHR15160:SF3; BIFUNCTIONAL NUCLEASE 1; 1.
DR   PANTHER; PTHR15160; VON HIPPEL-LINDAU PROTEIN; 1.
DR   Pfam; PF02577; BFN_dom; 1.
DR   SUPFAM; SSF103256; Hypothetical protein TM0160; 1.
DR   PROSITE; PS51658; BFN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000189703}.
FT   DOMAIN          122..257
FT                   /note="BFN"
FT                   /evidence="ECO:0000259|PROSITE:PS51658"
SQ   SEQUENCE   304 AA;  34101 MW;  8963453CA0D73DA9 CRC64;
     MGTLQGSVIC PTVRTKQAGV YTLPGNGPLM TAKILRSKLW GSKRRCRSRI NVEALSHPAL
     LQKSRTIHCS FRSSSNDNGS MAENFNENDE DYVNSSVVEA VEVKSSSDGF MIKMRDGRHL
     RCVHNNPQGG HLPDYAPHPA IVLKMEDGSG LLLPIIVLEM PSILLMAAVR NVPMARPTLY
     QVMKEMTETM GYEVKLVRVT KRVNEAYFAQ LYITKIDDET QRVSFDLRPS DAINIAVRCK
     VPIQVNKYLA YNDGMRVVEP AKMVSQPPLS DGLLFTNLDS YSLILRHLNL EECQLEIHER
     TLAL
//