ID A0A1U7ZQT8_NELNU Unreviewed; 565 AA.
AC A0A1U7ZQT8;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=anthranilate synthase {ECO:0000256|ARBA:ARBA00012266};
DE EC=4.1.3.27 {ECO:0000256|ARBA:ARBA00012266};
GN Name=LOC104596958 {ECO:0000313|RefSeq:XP_010256592.1};
GN ORFNames=HUJ06_028145 {ECO:0000313|EMBL:DAD26677.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010256592.1};
RN [1] {ECO:0000313|EMBL:DAD26677.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:DAD26677.1};
RX PubMed=32343808;
RA Shi T., Rahmani R.S., Gugger P.F., Wang M., Li H., Zhang Y., Li Z.,
RA Wang Q., Van de Peer Y., Marchal K., Chen J.;
RT "Distinct Expression and Methylation Patterns for Genes with Different
RT Fates following a Single Whole-Genome Duplication in Flowering Plants.";
RL Mol. Biol. Evol. 37:2394-2413(2020).
RN [2] {ECO:0000313|RefSeq:XP_010256592.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC tryptophan from chorismate: step 1/5. {ECO:0000256|ARBA:ARBA00004873}.
CC -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC beta subunit and a large alpha subunit.
CC {ECO:0000256|ARBA:ARBA00011653}.
CC -!- SIMILARITY: Belongs to the anthranilate synthase component I family.
CC {ECO:0000256|ARBA:ARBA00009562}.
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DR EMBL; DUZY01000002; DAD26677.1; -; Genomic_DNA.
DR RefSeq; XP_010256592.1; XM_010258290.1.
DR GeneID; 104596958; -.
DR OrthoDB; 705at2759; -.
DR UniPathway; UPA00035; UER00040.
DR Proteomes; UP000189703; Unplaced.
DR Proteomes; UP000607653; Unassembled WGS sequence.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR005256; Anth_synth_I_PabB.
DR InterPro; IPR015890; Chorismate_C.
DR NCBIfam; TIGR00564; trpE_most; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF9; ANTHRANILATE SYNTHASE COMPONENT 1; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Tryptophan biosynthesis {ECO:0000256|ARBA:ARBA00022822}.
FT DOMAIN 60..214
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 276..547
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 565 AA; 63512 MW; 0EB56C2ABBDA4179 CRC64;
MEFPFLSVSS RPTLSNLRLS QVFPVVAASR CAAASSGKTK FVEASKTANV VPMHRCLFSD
HLTPVLAYRC LVEESDPQAP SFVFDSFGKD SQSSVLGRYS VVGYQPTMEI IAEENRVTIL
NHVEGRRVEE LVEDPMVIPR RIMQGWRTPQ LMDKLPDTFC GGWVGYFSYD TVRYVEKKKL
PFSRAPEDDR NLPDVHLGLY DDVIVFDHVE KKAFVIHWVL LDRYSSVDEA YNDGMKRLQV
LVSKIQNIDP PRLSAGSIEL HTHHFGSSLK NSSMTSEAYK KAVVQAKEHI LSGDIFQIVL
SQRFERRTFA DPFEIYRALR VVNPSPYMAY LQARGCILVA SSPEILTRVK QRKITNRPLA
GTVRRGRTNK EDEILEEQLL NDEKQCAEHI MLVDLGRNDV GKVSKFGSVK VEKLMNIERY
SHVMHISSTV TGELLDDLTC WDALRAALPV GTVSGAPKVK AMELIDQLEV KRRGPYSGGF
GGICFSGDMD IALALRTMVF PTGARYDTMY SYKDSNKRRE WVAHLQAGAG IVADSNPDDE
QRECENKAAA LARAIDLAES TFIEK
//
