ID A0A1U7ZU50_NELNU Unreviewed; 1044 AA.
AC A0A1U7ZU50;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=LOC104597322 {ECO:0000313|RefSeq:XP_010257102.1};
GN ORFNames=HUJ06_028153 {ECO:0000313|EMBL:DAD26685.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010257102.1};
RN [1] {ECO:0000313|EMBL:DAD26685.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:DAD26685.1};
RX PubMed=32343808;
RA Shi T., Rahmani R.S., Gugger P.F., Wang M., Li H., Zhang Y., Li Z.,
RA Wang Q., Van de Peer Y., Marchal K., Chen J.;
RT "Distinct Expression and Methylation Patterns for Genes with Different
RT Fates following a Single Whole-Genome Duplication in Flowering Plants.";
RL Mol. Biol. Evol. 37:2394-2413(2020).
RN [2] {ECO:0000313|RefSeq:XP_010257102.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; DUZY01000002; DAD26685.1; -; Genomic_DNA.
DR RefSeq; XP_010257102.1; XM_010258800.2.
DR GeneID; 104597322; -.
DR KEGG; nnu:104597322; -.
DR eggNOG; ENOG502QPYS; Eukaryota.
DR OrthoDB; 382073at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR Proteomes; UP000607653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008:SF616; OS02G0211800 PROTEIN; 1.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 10.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|RefSeq:XP_010257102.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Receptor {ECO:0000313|RefSeq:XP_010257102.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 663..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 726..993
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 753
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1044 AA; 114331 MW; C29719DCA84024D5 CRC64;
MEFSPLRCVT LSLTMITHVL ILFSLNLFGL ESATAATTSG NDTDWLALLE FKKQITDDPL
GVLSSWNGSV HLCDWHGVTC GRRRRQRIIG LNLEGKKLVG TLSPHIGNLS LLSFINLQNN
SFHGSIPQEV SRLSMLRDIL LNNNSFGGEI PHNLSHCSNL KHLTLHYNRI EGKIPVELGS
LTHLVNLSLG SNNLTGGIPY SIGNLTSLEH LSFEGNSLGG NIPNIFNQMK RLKHLEFELN
DFFGIIPPSV YNLSSLTLIA LTGNKLNGSL RPNIGLAFPN LQFLWVGDNQ FSGPIPFSLS
NASGLIEIDI PGNNFTGPVP MDLGSIQTLQ WLGLGENPIG RGEADDLNFI TSLINCSDLW
TLSLYDCNFG GMLPSSIANL STQLIQLSFT GNQIIGGIPI GIENLVKLIS LEMDNNLLTG
SIPDSIGRLS KLQLLSLSGN RLTGQIPPSL GNMTQLVYLD LYNNNLRGRI PPSLVNCQGL
QEVYLSHNKL NGTIPKEVIG LSSLSIILDV SHNSLTGSLP LEVGSLKNLG HLDVSYNRMT
GEIPSTLGNC LSLEHLYMQG NFFQGTIPSS LSNLKAIQDL DLSNNNLSGS IPKSLGGLPL
LQYLNLSFNS FEGEVPVVGV FLNVTAVSVD GNRGLCGGIP ELKLQPCPME ESMKKGKSLT
FKLVTAIVSV ILGLTLILAL FFVCWRRKPK GISSSEPLVE ECSTPPFGEW YLKVSYRDLF
KATEGFSSGN LIGSGGYGTV YKGILHNNTI AVKVLNTQQR GASKSFMTEC EAVRNIRHRN
LIKIITACSS MDLNGNDFKA LVFEFMPNGS LEEWLHPGEE KNSQSRKLNF LVRLNIAIDV
ASALHYLHYQ CEAPIVHCDL KSSNVLLDND MTACVSDFGM SRLLSNSTKK LTQKQFSSFA
IKGTIGYAAP EYGMGAEVST HGDVYSYGIL LLEMFTGKRP TAEIFKDGLN LHNYCKMALS
ERVMEIADPL LLLYGEEIEQ NGEKETATNN EYLSGSGHKM QECLIFVIRI GVACSAELPR
ERMDMNEVTR EMNSIRNTFL GARY
//
