ID A0A1U7ZW95_NELNU Unreviewed; 586 AA.
AC A0A1U7ZW95;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Ankyrin repeat-containing protein ITN1 isoform X2 {ECO:0000313|RefSeq:XP_010253362.1};
GN Name=LOC104594664 {ECO:0000313|RefSeq:XP_010253362.1};
GN ORFNames=HUJ06_027432 {ECO:0000313|EMBL:DAD25964.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010253362.1};
RN [1] {ECO:0000313|EMBL:DAD25964.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:DAD25964.1};
RX PubMed=32343808;
RA Shi T., Rahmani R.S., Gugger P.F., Wang M., Li H., Zhang Y., Li Z.,
RA Wang Q., Van de Peer Y., Marchal K., Chen J.;
RT "Distinct Expression and Methylation Patterns for Genes with Different
RT Fates following a Single Whole-Genome Duplication in Flowering Plants.";
RL Mol. Biol. Evol. 37:2394-2413(2020).
RN [2] {ECO:0000313|RefSeq:XP_010253362.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DUZY01000002; DAD25964.1; -; Genomic_DNA.
DR RefSeq; XP_010253362.1; XM_010255060.2.
DR GeneID; 104594664; -.
DR OrthoDB; 5476624at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR Proteomes; UP000607653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03493; SQR_QFR_TM; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR026961; PGG_dom.
DR PANTHER; PTHR24186:SF48; ANKYRIN REPEAT-CONTAINING PROTEIN ITN1; 1.
DR PANTHER; PTHR24186; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13962; PGG; 1.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 413..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 158..181
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 226..258
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 260..292
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 294..327
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 408..514
FT /note="PGG"
FT /evidence="ECO:0000259|Pfam:PF13962"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 63526 MW; 7450B5F73CDFC939 CRC64;
MGSVIEEGER DLEKGQGLNP NPLAEPLHSP SPTSTSTAPA PALVLSNSGK RIDQAGKKKY
VKQVTGRHND TDLHLAAQRG DLVAVKQILN DIDAQMVGTL SGADFDAEVA EIRSAVVNEV
NELGENALFT AAEKGHLDVV KELLKYSTKE STSRKNNSGF DALHIAVSNG HQAVVQVLLD
HDPGLSKTVL PSNATPLITA ATRGHTAVVN ELLSKDSSLL EISRSNGKNA LHFAARQGHV
DIVKALLDKD PQLARRTDKK GQTALHLAVK GTNCEVVKLL LEADAAIVML PDRSGNTALH
VATRKKRAEI VNELLQLPDT NVNALNREHK TAFDIAEGLP LSEESSDMKE CLARCGAVRA
NELNQPRDEL RKTVTEIKKD VHTQLEQTRK TNKNVSGIAK ELRKLHREGI NNATNSVTVV
AVLFATVAFA AIFTVPGGDT DEGMAVVVGH ASFKIFFIFN AVALFTSLAV VVVQITLVRG
ETKSERRVVT VINKLMWLAS VCTSVAFIAS AYIVVGRHNH WAAILVTVVG GVVMAGVLGT
MTYYVVKYKR NRKIRRKEKK YSKRSASNSW PQSELSDSEV NPIYAI
//
