ID A0A1U7ZZJ6_NELNU Unreviewed; 1043 AA.
AC A0A1U7ZZJ6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=DNA mismatch repair protein MSH7 isoform X2 {ECO:0000313|RefSeq:XP_010254153.1};
GN Name=LOC104595228 {ECO:0000313|RefSeq:XP_010254153.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010254153.1};
RN [1] {ECO:0000313|RefSeq:XP_010254153.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010254153.1; XM_010255851.2.
DR AlphaFoldDB; A0A1U7ZZJ6; -.
DR GeneID; 104595228; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF153; DNA MISMATCH REPAIR PROTEIN MSH7; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703}.
FT DOMAIN 866..882
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1043 AA; 114874 MW; 49D6B73675AEC86D CRC64;
MQRQKSILSF FQKSSSESQS SDDSSYTDTL SRQHLVQFPR NQLKLNSSKS EQSNAPPSAK
DPWSEVRGTD TPPEKLPRRI FSTDLPANDD SRPSLFSSIL HKFARVDERE SSRDRNQANG
GSAGSYSTNI KIGDCQKLAL QGAPSQHSRK DNPSNSSVTY RGDVAHVESA PDILGPETPA
MRPLVPRLKR IQEDSSNLEE KNDSSLFDPN KRVKLLQDSE TANKNHRQAS EMTTSKFEWL
DPSLMRDAKG RRPGDALYDK RTLYIPPDAL KKMSASQKQY WSVKCQYMDV VLFFKVGKFY
ELYELDAEIG HKELDWKMTF SGVGKCRQVG ISESGIDDAV QKLLARGYKV GRIEQIETSN
QAKARGATSV IQRKLVHVMT PSTVVDGSIG PEAVHLLALK RGTGGLENGS VVYGFAFVDC
ATLKFWVGLI HDDASCAALG ALLMQVSPKE VIYEDTGLSR EAQKALKKYS VAGSTKLHLT
PMASITNFVD ESEVRKLIQN KGYFKGSTKL WDSVLDGGVH HDLTICALGG LVGNLSRLKL
DDVLCNGDVL PYQVYKGCLR MDGQTLVNLE IFSNNADGGQ SGTLYKYLDN CTTSSGKRLL
RSWICHPLRD VGDIDSRLNV VEELVTHSEI TSLVAQYLRK IPDIERLLGR VKATVGSSAS
LLLPMVGEKV LKQRDHDVTE SDAETLSLLV ELFIEKDTEW SQVIHALNCI DVLQSFAVAA
NSSCGSMCRP VVLPANSRSV TACRDIGAPV LKIRGLWHPY ALGESGATLV PNDVHLGEDT
NGYCPQALLL TGPNMGGKST LLRATCLAVI LAQLGCYVPC EMCVMSPADI IFTRLGATDR
IMTGESTFLI ECMETASVLQ HATQESLVLL DELGRGTSTF DGYAIAYAVF RHLIEKVHCR
LLFATHYHPL TKEFASHPRV SLQHMACSFK SKSCSSKDDE ELVFLYRLTS GACPESYGLQ
VALMAGIPRE VVAVASKASQ AMKQSIGQSF KSSECRSEFS SLHEEWLKTL LAVARAGHCS
LADDDVFDTL LCLWHELKSL YCL
//
