ID A0A1U8A7Q0_NELNU Unreviewed; 360 AA.
AC A0A1U8A7Q0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Methyl-CpG-binding domain-containing protein 2-like {ECO:0000313|RefSeq:XP_010263335.1};
GN Name=LOC104601621 {ECO:0000313|RefSeq:XP_010263335.1};
GN ORFNames=HUJ06_004431 {ECO:0000313|EMBL:DAD46201.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010263335.1};
RN [1] {ECO:0000313|EMBL:DAD46201.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:DAD46201.1};
RX PubMed=32343808;
RA Shi T., Rahmani R.S., Gugger P.F., Wang M., Li H., Zhang Y., Li Z.,
RA Wang Q., Van de Peer Y., Marchal K., Chen J.;
RT "Distinct Expression and Methylation Patterns for Genes with Different
RT Fates following a Single Whole-Genome Duplication in Flowering Plants.";
RL Mol. Biol. Evol. 37:2394-2413(2020).
RN [2] {ECO:0000313|RefSeq:XP_010263335.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DUZY01000007; DAD46201.1; -; Genomic_DNA.
DR RefSeq; XP_010263335.1; XM_010265033.2.
DR STRING; 4432.A0A1U8A7Q0; -.
DR GeneID; 104601621; -.
DR KEGG; nnu:104601621; -.
DR eggNOG; KOG4161; Eukaryota.
DR OrthoDB; 1217115at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR Proteomes; UP000607653; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01396; MeCP2_MBD; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR12396:SF0; METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C; 1.
DR PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 107..166
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 172..246
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 40398 MW; 838D487DC008B8DC CRC64;
MQTFHGDAPP KLKENELTES SSLSHLDDTI QQPGYYSPLE GEEEDDVQFL EDEYDQFNGN
TSNQLVVYNP EVTDTDQSEL ANDADLDGYQ LQPLSIYTKP NPPSRILPSV GAFTVQCANC
FKWRLIPTKE KYEEIRETIL QNPFVCETAC AWRPGITCDD PTDISQDGSR LWAIDKPNIA
QPPPGWERLL RIRGEGSTRF ADIYYVAPSG KRLRSMVEIQ RYLLEHPEYT DAGVTMSQFS
FQIPKPLQEN YVRKRPPGPP RVAPSYDGSG LGISSPLEPT DVNPLSWADP ADSPELQLGG
PGLSTPYVEV PIFDPEARPT KKRTTKSLSK DIYGNSPLYD CQFKTEEPER LKSGTTDLSL
//
