ID A0A1U8AAS7_NELNU Unreviewed; 647 AA.
AC A0A1U8AAS7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein VASCULAR ASSOCIATED DEATH 1, chloroplastic-like {ECO:0000313|RefSeq:XP_010258771.1};
GN Name=LOC104598421 {ECO:0000313|RefSeq:XP_010258771.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010258771.1};
RN [1] {ECO:0000313|RefSeq:XP_010258771.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR RefSeq; XP_010258771.1; XM_010260469.2.
DR AlphaFoldDB; A0A1U8AAS7; -.
DR STRING; 4432.A0A1U8AAS7; -.
DR GeneID; 104598421; -.
DR KEGG; nnu:104598421; -.
DR eggNOG; KOG1032; Eukaryota.
DR InParanoid; A0A1U8AAS7; -.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043069; P:negative regulation of programmed cell death; IBA:GO_Central.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47666:SF1; TBC1 DOMAIN FAMILY MEMBER 9B ISOFORM X1; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 551..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 290..461
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 73551 MW; 1A32582FF056FBD4 CRC64;
MAVASPSKEK AEPSQSIESI PSSPLVSKSG SDSGSETSSL GVVDPSDRNE QSDSSVNHRK
DVEIQSAASL RSEEYRQLFR LPPDEVLVQD FNCALQENIL LQGHMYLFVH HICFYSNIFG
FETKKIITFH EVTCVRKAKT AAIFPNAIEI LAGGKKYFFA SFLSRDEAYR LIVDGWAQHN
DRVNAQIDCQ ESKSDNGSQD ALVIFENSKS FKRQTNDLYS MDRNKDSRVL EECNRLSNGE
DDISVSTRHS ETLENGEEDL EPVANAETLL SRKPFIWKPE DANAPKIPEC YTLVAESKFP
IQLEEFFNLF FSDEAVNFLE SFHTRCGAKE FRCTSWYEEQ FGYARDVSFQ HPIKLYFGAR
YGHCQGIQKV RVYRDRHMIV ETSQEISDVP YGDYFRVQGL WDVKSTGDEG NSYCILHVYI
NVAFSKKTMW RGKIEQSTAD ECRDAYSIWI NNAHELLKQK HLTRQEDRAA NGVETDAAQV
DRHTKIEESS EGLHDARNHA GHPQLASDSM DSNRQFGNPL QGILNDTTSV SSLSKELLTT
LCSYLRSRSH LPLILVITSV LILLLMQLSI VVLLTRAPQV HIIPQVDYIN SIGSRGNGAE
EIALLEKRVH LLSDEMVVVG TRLEKLHQEY LELKARLHDL KQFKKQR
//
