ID A0A1U8AJ36_NELNU Unreviewed; 919 AA.
AC A0A1U8AJ36;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN Name=LOC104604850 {ECO:0000313|RefSeq:XP_010267706.1};
GN ORFNames=HUJ06_024799 {ECO:0000313|EMBL:DAD23336.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010267706.1};
RN [1] {ECO:0000313|EMBL:DAD23336.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:DAD23336.1};
RX PubMed=32343808;
RA Shi T., Rahmani R.S., Gugger P.F., Wang M., Li H., Zhang Y., Li Z.,
RA Wang Q., Van de Peer Y., Marchal K., Chen J.;
RT "Distinct Expression and Methylation Patterns for Genes with Different
RT Fates following a Single Whole-Genome Duplication in Flowering Plants.";
RL Mol. Biol. Evol. 37:2394-2413(2020).
RN [2] {ECO:0000313|RefSeq:XP_010267706.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; DUZY01000001; DAD23336.1; -; Genomic_DNA.
DR RefSeq; XP_010267706.1; XM_010269404.2.
DR GeneID; 104604850; -.
DR KEGG; nnu:104604850; -.
DR eggNOG; KOG1052; Eukaryota.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR Proteomes; UP000607653; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF427; GLUTAMATE RECEPTOR 3.7; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 837..860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..816
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
SQ SEQUENCE 919 AA; 102564 MW; D219865B2E83358A CRC64;
MGLHRIKTMG TALLVSFFVS MWVLLSGFVY CQRPAVVNVG AVFTYDSVIG RDAKVAMEAA
VADINADQSI LNGTRLNLIM ADAQCNVFLG SIGAFQVLEK EAVAIIGPQS STIAHMISFI
ANGLQVPLIS YASTDPSLSA LQFPFFVRST QSDAYQMTAM ADLIGYYGWR EVIAIFADDE
YGRSGISSLD NELTKQMSKI SYKLAWPTGS NLSYITDLLN KTKLIGTRVF VVHANPDSGI
AIFSVAQDLQ MMTNGYVWIA TDWLCATLDS SPLMNQTSLQ NLQGVVGLCQ HTPQSLRKKA
FVSRWKHMFQ KGLVSYGLNT YGLYAYDTVW AVARSIDDFL NDYGNITFSF NKALRGMQTS
SLKLGKLRTF DGGTLLRSKL LQMNFTGLTG PVRFDSDRNL IGAGYDIINI DEKTIRRIGY
WSNYSGLSVV PPETLKRGQR HGSLLDQKLK NVTWPGKRTE KPRGWVIGDN GRPLRIGVPY
RASFVEFVTE IHGTKDFQGY CIDVFTAARE LVPYDIPYKF VAFGDGKSNP SYDEFVRMVA
ENVIDGAVGD ITIVTNRMKI TDFTQPYAAT GLVIVAPISN GKSSAWVFLK PFTVDMWCVT
ASFFILIGVV IWILEHRIND DFRGPPRRQL ITMFLFSFST LFKTNKEQTL SALGRMVMMV
WLFLLMVITS SYTANLTSIL TIQKLTSPIT GLDSLTTSRW PIGYQVGSFA RSYMIDNFNI
PESRLVSLGS PEDYERALRL GPGNGGVAAI VDELPYVELF LSNRTDFGIV GEMFTKNGWG
FAFPRDSPLA IDMSTAILRL SENGELHKIH KKWFCQMGCT EGQGHQSKSN QLHMISFWGL
FLLCGIVTII ALLVFLARMV RQFVQYKRKQ RDLSSASSSE SSSAHCSQII YNFFDFIDEK
EEATKKMFKQ CDNPQPQAS
//
