ID A0A1U8AK84_NELNU Unreviewed; 911 AA.
AC A0A1U8AK84;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN Name=LOC104604850 {ECO:0000313|RefSeq:XP_010267707.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010267707.1};
RN [1] {ECO:0000313|RefSeq:XP_010267707.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR RefSeq; XP_010267707.1; XM_010269405.2.
DR AlphaFoldDB; A0A1U8AK84; -.
DR GeneID; 104604850; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF427; GLUTAMATE RECEPTOR 3.7; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..911
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010566798"
FT TRANSMEM 588..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 829..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 465..808
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
SQ SEQUENCE 911 AA; 101627 MW; DA195AC6D7A1AC79 CRC64;
MGTALLVSFF VSMWVLLSGF VYCQRPAVVN VGAVFTYDSV IGRDAKVAME AAVADINADQ
SILNGTRLNL IMADAQCNVF LGSIGAFQVL EKEAVAIIGP QSSTIAHMIS FIANGLQVPL
ISYASTDPSL SALQFPFFVR STQSDAYQMT AMADLIGYYG WREVIAIFAD DEYGRSGISS
LDNELTKQMS KISYKLAWPT GSNLSYITDL LNKTKLIGTR VFVVHANPDS GIAIFSVAQD
LQMMTNGYVW IATDWLCATL DSSPLMNQTS LQNLQGVVGL CQHTPQSLRK KAFVSRWKHM
FQKGLVSYGL NTYGLYAYDT VWAVARSIDD FLNDYGNITF SFNKALRGMQ TSSLKLGKLR
TFDGGTLLRS KLLQMNFTGL TGPVRFDSDR NLIGAGYDII NIDEKTIRRI GYWSNYSGLS
VVPPETLKRG QRHGSLLDQK LKNVTWPGKR TEKPRGWVIG DNGRPLRIGV PYRASFVEFV
TEIHGTKDFQ GYCIDVFTAA RELVPYDIPY KFVAFGDGKS NPSYDEFVRM VAENVIDGAV
GDITIVTNRM KITDFTQPYA ATGLVIVAPI SNGKSSAWVF LKPFTVDMWC VTASFFILIG
VVIWILEHRI NDDFRGPPRR QLITMFLFSF STLFKTNKEQ TLSALGRMVM MVWLFLLMVI
TSSYTANLTS ILTIQKLTSP ITGLDSLTTS RWPIGYQVGS FARSYMIDNF NIPESRLVSL
GSPEDYERAL RLGPGNGGVA AIVDELPYVE LFLSNRTDFG IVGEMFTKNG WGFAFPRDSP
LAIDMSTAIL RLSENGELHK IHKKWFCQMG CTEGQGHQSK SNQLHMISFW GLFLLCGIVT
IIALLVFLAR MVRQFVQYKR KQRDLSSASS SESSSAHCSQ IIYNFFDFID EKEEATKKMF
KQCDNPQPQA S
//
