ID A0A1U8AX54_NELNU Unreviewed; 982 AA.
AC A0A1U8AX54;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=MDIS1-interacting receptor like kinase 2-like {ECO:0000313|RefSeq:XP_010267605.1};
GN Name=LOC104604780 {ECO:0000313|RefSeq:XP_010267605.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010267605.1};
RN [1] {ECO:0000313|RefSeq:XP_010267605.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010267605.1; XM_010269303.2.
DR AlphaFoldDB; A0A1U8AX54; -.
DR KEGG; nnu:104604780; -.
DR eggNOG; ENOG502QVR7; Eukaryota.
DR InParanoid; A0A1U8AX54; -.
DR OrthoDB; 372969at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR48005; LEUCINE RICH REPEAT KINASE 2; 1.
DR PANTHER; PTHR48005:SF16; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 6.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 9.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|RefSeq:XP_010267605.1};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Receptor {ECO:0000313|RefSeq:XP_010267605.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|RefSeq:XP_010267605.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..982
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013024729"
FT TRANSMEM 624..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 690..962
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 719
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
FT UNSURE 691
FT /note="D or N"
FT /evidence="ECO:0000313|RefSeq:XP_010267605.1"
SQ SEQUENCE 982 AA; 108155 MW; 56F9980CD3092E5A CRC64;
MADFDKYVSL VLLVFAWFLL PSCSAQEPPS SEADALLRWK ASLQSQTVLQ SWTTTATRPN
ATTSPNPCNW TGIACNKAGN VTEINLFKAA LQGKLDNFDF SSFPNLLRLD LSDNQLSGTI
PTHIGKLTRL TYLDLSVNQL SGVLPLSLAN LSNLSELYLS NNALTGELHP HLFSNWTRLT
NLDLQYNNLT GRIPREITLL TSLRELVLMS NQISGSIPSE IGDVKNLEKL LLRGNNLIGT
IPPSLGNLTK LTHLFLDLNH LSGSIPPTIG IWRSLTDLRL CRNRLSGVVP QEIGNLSLLT
VFHMNYDNFS GHLPQQLCKN GLLVNFTAAG NNFTGPIPEG LRNCPTLYRF RLEGNQLTGS
IDRDLGAYPN LDYIDLSNNK LNGELSPSWG RCRNLTAVKL AGNNIQGTIP VEFGQLTKLG
VLDLSSNQLV GEIPKQVVRL SSLIRLSLKD NHLSGQIPFE TGELSNLNFL DMSMNMLSGP
IPEQIGDCSR LQHLSLSKNL FNGTIPYTIG NLVDLQELLD LSENSLTGEI PSQFKKLTKL
MNLNLSHNML TGVIPFSLSE MDSLTSIDLS YNDLEGPLPN SRAFQQSPPA AFANNRGLCC
ESCGLQACNL SSTEEGDRRT NFKFVIVIVA SCSVALFFLV LFIGFSGFCQ KISKSEKTGA
SVAGNGHIFS VWNYDGRIMY EDIIRATEGF DNKYCIGIGR SGKVYKAQLS NDHVLAIKKL
SSEESELENV KSFRNEMQVL TETRHRNIVK LYGFCCHLDH TFLVYEYMEN GSLSNILSSD
NSAKKLDWIK RIKIVAGVAQ ALSYMHHDCK PPIVHRDISS KNVLLNTQLE ACVSDFGTAK
FLKPDSSNWT TVAGTYGYIA PELAYTMVVT EKCDVYSFGV LVLEVIMGKH PGELISSLSS
SSDEDIVLKH VMDPRLSPPT IPQVSKALAS IMMLALACLN ADPQSRPTMR HTAQELLGHD
LSFTKLFGST DVGSPSHGSR YL
//
