ID   A0A1U8AXQ8_NELNU        Unreviewed;       777 AA.
AC   A0A1U8AXQ8;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Subtilisin-like protease SBT3.9 isoform X1 {ECO:0000313|RefSeq:XP_010271498.1};
GN   Name=LOC104607534 {ECO:0000313|RefSeq:XP_010271498.1};
OS   Nelumbo nucifera (Sacred lotus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX   NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010271498.1};
RN   [1] {ECO:0000313|RefSeq:XP_010271498.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR   RefSeq; XP_010271498.1; XM_010273196.2.
DR   AlphaFoldDB; A0A1U8AXQ8; -.
DR   GeneID; 104607534; -.
DR   KEGG; nnu:104607534; -.
DR   eggNOG; ENOG502QSF0; Eukaryota.
DR   InParanoid; A0A1U8AXQ8; -.
DR   OrthoDB; 11910at2759; -.
DR   Proteomes; UP000189703; Unplaced.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd02120; PA_subtilisin_like; 1.
DR   CDD; cd04852; Peptidases_S8_3; 1.
DR   Gene3D; 2.60.40.2310; -; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR034197; Peptidases_S8_3.
DR   InterPro; IPR010259; S8pro/Inhibitor_I9.
DR   InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR   InterPro; IPR045051; SBT.
DR   InterPro; IPR041469; Subtilisin-like_FN3.
DR   PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR   PANTHER; PTHR10795:SF818; SUBTILISIN-LIKE PROTEASE SBT3.9 ISOFORM X1; 1.
DR   Pfam; PF17766; fn3_6; 1.
DR   Pfam; PF05922; Inhibitor_I9; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}.
FT   DOMAIN          28..110
FT                   /note="Inhibitor I9"
FT                   /evidence="ECO:0000259|Pfam:PF05922"
FT   DOMAIN          138..593
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
FT   DOMAIN          671..766
FT                   /note="Subtilisin-like protease fibronectin type-III"
FT                   /evidence="ECO:0000259|Pfam:PF17766"
FT   ACT_SITE        144
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        219
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        556
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   777 AA;  82998 MW;  D215CC4CC6263A31 CRC64;
     MASSCRLLLV LPLLLQRFIF LLISASNVHI VYMGERRHHD YQLTQDSHHE ILSTLLGSKQ
     AARESILYSY KHGFSGFAAL LTQSQAKLIA VNVDFPGVVR VIPNRILRVH TTRSWDFLQL
     KPEIMDGILS RSQSGYDSII GVLDTGIWPE SESFKDDGMG EVPSRWNGVC QEGEEFNASN
     CNRKVIGARW YIKGYAAEFG KLNTSGDVEF LSPRDAVGHG THTSSTAAGA LVGNASFMGL
     AQGLARGGAP AARLSIYKVC WSTGGCSSAD LLAAFDDAIS DGVDVLSVSL GSPPPLSPYI
     EDALAIGSFH VVAKGIPVVC SGGNSGPSSQ TVINTAPWII TVAASTIDRS FPTTIILGNN
     LSLVGQALLT EKHVNKFYPI VYGESIASND SDEDKARSCD AGSLNATLAR GKVVLCFQSR
     LKGSASIATK TVARVRGVGV IFAQFPTKDI ASTSGIPCVQ VDYTIGTSVL TYIESTRNPV
     VRFSLTTTSL GRQISPEVAF FSSRGPSSIS PSVLKPDIAA PGVNILASWS PASSLSPGVH
     RHKQPSLKFK IESGTSMSCP HVSGIVALLK SMHPNWSPAA IKSALVTTAS TKDKYGQSAV
     AEGSPHKQAD PFDYGGGHVD PNKAADPGLI YDMGITDHVR FLCLMGYNDS SVSLMTRHPT
     VCSKTSKSLA DLNLPSISIP ELKKSLAVSR TVTNVGPVNS VYSVHVKAPP GVIVHVNPSV
     LSFNSTAKQL RFKVTFQSQL SVQGRYSFGS LSWEDGIHVV RIPLIVRTVI DDFYADI
//