ID A0A1U8AZL6_NELNU Unreviewed; 722 AA.
AC A0A1U8AZL6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN Name=LOC104608057 {ECO:0000313|RefSeq:XP_010272222.1,
GN ECO:0000313|RefSeq:XP_010272223.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010272223.1};
RN [1] {ECO:0000313|RefSeq:XP_010272222.1, ECO:0000313|RefSeq:XP_010272223.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR RefSeq; XP_010272222.1; XM_010273920.2.
DR RefSeq; XP_010272223.1; XM_010273921.2.
DR GeneID; 104608057; -.
DR OrthoDB; 20951at2759; -.
DR UniPathway; UPA00591; UER00663.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR CDD; cd01319; AMPD; 1.
DR Gene3D; 4.10.800.20; -; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR006650; A/AMP_deam_AS.
DR InterPro; IPR006329; AMPD.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01429; AMP_deaminase; 1.
DR PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR PANTHER; PTHR11359:SF14; AMP DEAMINASE; 1.
DR Pfam; PF19326; AMP_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR PROSITE; PS00485; A_DEAMINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189703}.
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 83078 MW; 570A4A9E683D2DC6 CRC64;
MRLASLGRPT TPRSPGGNAF ESVEDSDEEG TELPYGEDNL VSYDNTSSAP VDTNVHGADP
NIQDSSVSLQ VENVNSSQDP MCGETVSSLL SDAKEPDAAE MLIVQKDSAC TLVPLKTISH
EVPNGEEEEV CAMIRECLSL RERYVYRECV APWMKETIAE SCPPGIHKDP FHFDPVEPTG
HHFKMEDGVA HVYASKEATE ELYPVASSTT FFTDMHYILR IMSLGNVRSI CYHRLRFLEE
KFRLHLLINA DREFLAQKGA PHRDFYNVRK VDTHVHHSAC MNQKHLLRFI KSKLRKEPDE
VVIFRDGKYL TLKEVFESLD LTGYDLNVDL LDVHADKSTF HRFDKFNLKY NPCGQSRLRE
IFLKQDNLIQ GRFLAEVTKQ VLSDLEASKY QMAEYRISIY GRKQSEWDQM ASWFTNNAIY
SENAVWLIQL PRLYNVYRQM GIVTSFQNIL DNVFIPLFEV TVDPNSHPQL HVFLMQVVGF
DIVDDESKPE RRPTKHMPKP AEWTNEFNPA YSYYAYYCYA NLCTLNKLRE SKGMPTIRFR
PHCGEAGDID HLAAAFLLCH NISHGINLRR SPVLQYLYYL TQIGLAMSPL SNNSLFLDYH
RNPFPMFFQR GLNVSLSTDD PLQIQLTKEP LVEEYSVAAQ VWKLTSCDLC EVARNSVYQS
GFSHAAKMHW LGNKYFKRGP EGNDIHKTNV PRMRIAFRHE TWEEEMQYVY LGKASIPEEI
AY
//
