ID A0A1U8B5R2_NELNU Unreviewed; 909 AA.
AC A0A1U8B5R2;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Extra-large guanine nucleotide-binding protein 3-like isoform X1 {ECO:0000313|RefSeq:XP_010271180.1};
GN Name=LOC104607272 {ECO:0000313|RefSeq:XP_010271180.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010271180.1};
RN [1] {ECO:0000313|RefSeq:XP_010271180.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010271180.1; XM_010272878.2.
DR AlphaFoldDB; A0A1U8B5R2; -.
DR STRING; 4432.A0A1U8B5R2; -.
DR GeneID; 104607272; -.
DR KEGG; nnu:104607272; -.
DR eggNOG; KOG0082; Eukaryota.
DR InParanoid; A0A1U8B5R2; -.
DR OrthoDB; 1221906at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218:SF317; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3-LIKE; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 98..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 102731 MW; D691CF3A8509B320 CRC64;
MAAEPEMEKK WEEVLRKMLP AGAPLPDEEH LDYSIAVEYR GPPVLYEVPK VEPLDFDSLS
IRSSSLVSVS EYAPVVRVVA PVILAAPKAS RFNGILNGEG SGELGKSPQV ESPRSLGSTR
AQTEFRGDGS RELDWGGEGA EEGLSPASSP SLWEGNSVSD SPFVGSPKTT VGGRRTAVVA
FNTADQWVDE EDELASTRSS VVDQEVVPVV VQRKRGVCSR CGKGNILKER EACLVCDARY
CSNCVLKAMG SMPEGRKCVS CIGKPINELK RSSLGKSSRM LCRLCSPLEV RQIMKAEKEC
SANQLRPEQL IVNGRPLRQE ELAEVLGCAY PPQKLKPGRY WYDKDSGLWG KEGEKPDKII
SSKLNVGGKL QSEASNGNTQ VYINGREIPK IELRMLKLAK VQCPRDTHFW VYADGSYEEE
GQNNIKGKIW EKVYFHLLIQ VTLTWFNFEI LNPAMGFSGQ ASTRFLCSLF SLPVPPRNAT
GQGEDAANFS SRSVPEYLEQ RKVQKLLLHG LEGSGTSTIF KQAKFLHGNF TSEEQHDMKL
MIQRNMYKYL SVLLEGREHF EEEALMRRDA TFDAEESGQE SGCDESKQCI YAINQRLKHF
SDWLLEIMAT GDLDAFFPAA TREYAPVVDE VWKDPAIQET YKRRDELHFL PDVANYFLNR
AIEISSNEYE PSEKDILYAE GVTQSNGVAF LEFMLDDHSP MSEIYNENFE CPQTNQRYQL
IRVNSKGLGD GCKWLEMFED VRAVLFCVAL SDYDQLRAQG MGPVCNRMLA SRDLFESVVR
HPCFRDTPFI LLLNKYDAFE EKINRVPLTV CEWFGDFSPV KPHHNNQSLA NQAYFYVAMK
FKNLYTSITN GKLFVAQTRA HERSTVDDAF KYTREILKWE DEKDDKYVIN GEDSFYSTEI
SSSPYIRQE
//
