ID A0A1U8B6I0_NELNU Unreviewed; 481 AA.
AC A0A1U8B6I0;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=La protein 1 {ECO:0000313|RefSeq:XP_010271823.1};
GN Name=LOC104607803 {ECO:0000313|RefSeq:XP_010271823.1};
OS Nelumbo nucifera (Sacred lotus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Nelumbonaceae; Nelumbo.
OX NCBI_TaxID=4432 {ECO:0000313|Proteomes:UP000189703, ECO:0000313|RefSeq:XP_010271823.1};
RN [1] {ECO:0000313|RefSeq:XP_010271823.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
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DR RefSeq; XP_010271823.1; XM_010273521.2.
DR AlphaFoldDB; A0A1U8B6I0; -.
DR STRING; 4432.A0A1U8B6I0; -.
DR GeneID; 104607803; -.
DR KEGG; nnu:104607803; -.
DR eggNOG; KOG0118; Eukaryota.
DR InParanoid; A0A1U8B6I0; -.
DR OrthoDB; 5477115at2759; -.
DR Proteomes; UP000189703; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005844; C:polysome; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd08030; LA_like_plant; 1.
DR CDD; cd12291; RRM1_La; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045180; La_dom_prot.
DR InterPro; IPR006630; La_HTH.
DR InterPro; IPR014886; La_xRRM.
DR InterPro; IPR002344; Lupus_La.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22792:SF140; LA-RELATED PROTEIN 7; 1.
DR PANTHER; PTHR22792; LUPUS LA PROTEIN-RELATED; 1.
DR Pfam; PF05383; La; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF08777; RRM_3; 1.
DR PRINTS; PR00302; LUPUSLA.
DR SMART; SM00715; LA; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50961; HTH_LA; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS51939; XRRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189703};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00332}.
FT DOMAIN 4..109
FT /note="HTH La-type RNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS50961"
FT DOMAIN 116..201
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 334..462
FT /note="XRRM"
FT /evidence="ECO:0000259|PROSITE:PS51939"
FT REGION 246..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 53039 MW; 1C093D81C33BF0C0 CRC64;
MATAPLDEET SKKVLRQVEF YFSDSNLPRD NFLKKSVSES EDGMVSLALI CSFSRMRSHL
GLGDLKPDDV SEETVRAVAQ TLRNSASLKV SEDGKKVGRS TELLKPEEVI EQVNIRTIAA
SPLEYNVKLE EVESFFDKYG KVNSVRLPRH IADKKVFCGS ALIEFSSEED AENVLKQSLI
YAGTELKLKP KKDFDAERAK MVDEYENSRS STGSKFKNNS STSGNYPKGL IIAFKLKKVS
GGQGDILKTA DDNGDACKTG EELDSKENSV EVSGQEASRS DKDVEEKPLH DVEAERGEVT
AKVDEGSAEK ESGEAVHEAE KKPPEDASQE CNVKASGGEI TKATMYKDNN DVVLREDLKD
VFNRFGTVKF VDYRIGEESG YIRFEAPEAA QKARAAAVLA DEGGLIVKNY IATLEAVTGE
AETEYWNLLR GNQERHRESK FNRGRGGKNG RGGRHFGGKH ARSRENDSVG RPNKTQKVAV
A
//
