ID A0A1U8BHH7_MESAU Unreviewed; 891 AA.
AC A0A1U8BHH7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Receptor-type tyrosine-protein phosphatase kappa isoform X14 {ECO:0000313|RefSeq:XP_012965640.1};
GN Name=Ptprk {ECO:0000313|RefSeq:XP_012965640.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012965640.1};
RN [1] {ECO:0000313|RefSeq:XP_012965640.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_012965640.1; XM_013110186.2.
DR AlphaFoldDB; A0A1U8BHH7; -.
DR OrthoDB; 2875525at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 2.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR24051:SF11; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR PANTHER; PTHR24051; SUSHI DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00629; MAM; 1.
DR PRINTS; PR00020; MAMDOMAIN.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00137; MAM; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00740; MAM_1; 1.
DR PROSITE; PS50060; MAM_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_012965640.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..891
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010554960"
FT TRANSMEM 755..776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..195
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 197..282
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 295..390
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 492..596
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 891 AA; 99460 MW; DB68BE5675527D99 CRC64;
MDVAAAAAAL PAFVALWLLS PWPLLGSVQG QFTAGGCTFD DGPGACDYHQ DLYDDFEWVH
VSAQEPHYLP PEMPQGSYMV VDSSNHDPGE KARLQLPTMK ENDTHCIDFS YLLYSQKGLN
PGTLNILVRV NKGPLANPIW NVTGFTGRDW LRAELAVSTF WPNEYQVIFE AEVSGGRSGY
IAIDDIQVLS YPCDKSPHFL RLGDVEVNAG QNATFQCIAT GRDAVHNKLW LQRRNGEDIP
VAQTKNINHR RFAASFRLQE VTKTDQDLYR CVTQSERGSG VSNFAQLIVR EPPRPIAPPQ
LLGVGPTYLL IQLNANSIIG DGPIILKEVE YRMTSGSWTE THAVNAPTYK LWHLDPDTEY
EIRVLLTRPG EGGTGLPGPP LITRTKCAEP MRTPKTLKIA EIQARRIAVD WESLGYNITR
CHTFNVTICY HYFRGHNESR ADCLDMDPKA PQHVVNHLPP YTNVSLKMIL TNPEGRKESE
ETIIQTDEDV PGPVPVKSLQ GTSFENKIFL NWKEPLEPNG IITQYEVSYS SIRSFDPAVP
VAGPPQTVSN LWNSTHHVFM HLHPGTTYQF FIRASTVKGF GPATAINVTT NISAPTLPDY
EGVDASLNET ATTITVLLRP AQAKGAPISA YQIVVEQLHP HRTKREAGAM ECYQVPVTYQ
NAMSGGAPYY FAAELPPGNL PEPAPFTVGD NRTYKGFWNP PLAPRKGYNI YFQAMSSVEK
ETKTQCVRIA TKAAATEEPE VIPDPAKQTD RVVKIAGISA GILVFILLLL VVIVIVKKRY
ICWRRHICIR NIRRSYYSYS YYLKLAKKRK DAMGNTRQEM THMVNAMDRS YADQSTLHAE
DPLSLTFMDQ HNFSPRLPND PLVPTAVLVP ITGRKSVYHG DNNSFFAISY L
//
