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Database: UniProt
Entry: A0A1U8BNI4_MESAU
LinkDB: A0A1U8BNI4_MESAU
Original site: A0A1U8BNI4_MESAU 
ID   A0A1U8BNI4_MESAU        Unreviewed;       419 AA.
AC   A0A1U8BNI4;
DT   10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT   10-MAY-2017, sequence version 1.
DT   16-OCT-2019, entry version 18.
DE   SubName: Full=inward rectifier potassium channel 16 {ECO:0000313|RefSeq:XP_012968926.1, ECO:0000313|RefSeq:XP_012968927.1};
GN   Name=Kcnj16 {ECO:0000313|RefSeq:XP_012968926.1,
GN   ECO:0000313|RefSeq:XP_012968927.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012968926.1};
RN   [1] {ECO:0000313|RefSeq:XP_012968926.1, ECO:0000313|RefSeq:XP_012968927.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_012968926.1; XM_013113472.1.
DR   RefSeq; XP_012968927.1; XM_013113473.1.
DR   STRING; 10036.XP_005070027.1; -.
DR   Ensembl; ENSMAUT00000027045; ENSMAUP00000023039; ENSMAUG00000020304.
DR   GeneID; 101832969; -.
DR   CTD; 3773; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000189706; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR008061; K_chnl_inward-rec_Kir5.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF24; PTHR11767:SF24; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01678; KIR5CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000189706};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_012968926.1,
KW   ECO:0000313|RefSeq:XP_012968927.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     74     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       38    174       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      182    348       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        161    161       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   419 AA;  47820 MW;  782978A8321ABA13 CRC64;
     MSYYGSSYRV VNVDSKYPGY PPEHAIAEKR RARRRLLHKD GSCNVYFKHI FGEWGSYMVD
     IFTTLVDTKW RHMFVIFSLS YILSWLIFGS IFWLIAFHHG DLLNDPGITP CVDNVHSFTA
     AFLFSLETQT TIGYGYRCVT EECSVAILTV ILQSILSCII NTFIIGAALA KMATARKRAQ
     TIRFSYFALI GMRDGKLCLM WRIGDFRPNH VVEGTVRAQL LRYSEDSEGR MTMAFKDLKL
     VNDQIILVTP VTIVHEIDQE SPLYALDRKA VAKDNFEILV TFIYTGDSTG TSHQSRSSYV
     PREILWGHRF NDVLEVKRKY YKVNCLQFEG SVEVYAPFCS AKQLDWKDQQ LTNLEKTSPA
     RGSCTSDASV KRRSFSAVAI VSNCENPQET STSPPDEHKE VPYQKAILTL NRISMESQM
//
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