ID A0A1U8BUT6_MESAU Unreviewed; 1584 AA.
AC A0A1U8BUT6;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Sorbin and SH3 domain-containing protein 1 isoform X18 {ECO:0000313|RefSeq:XP_012971021.2};
GN Name=Sorbs1 {ECO:0000313|RefSeq:XP_012971021.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012971021.2};
RN [1] {ECO:0000313|RefSeq:XP_012971021.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26319212;
RA Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT "Transcriptome sequencing and development of an expression microarray
RT platform for liver infection in adenovirus type 5-infected Syrian golden
RT hamsters.";
RL Virology 485:305-312(2015).
RN [2] {ECO:0000313|RefSeq:XP_012971021.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012971021.2; XM_013115567.2.
DR STRING; 10036.ENSMAUP00000025049; -.
DR Proteomes; UP000189706; Unplaced.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 202..259
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 1048..1107
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1122..1183
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1523..1584
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..840
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1325..1396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1490..1522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..255
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..840
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..923
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1340..1369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1370..1386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1497..1522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1584 AA; 174849 MW; E93C866B0D823248 CRC64;
MSSECDVGSS KAVVNGLAPG SHVQDKDMDP TKICTGKGTV TLRASSSYRE TPSSSPVSPQ
ESPKHESKSG LEPEEDPSAD ERRLSSSADA NGNAQPSPLA AKGYRSVHPS LSTDKPQGSP
LINEVSSSHI ETDSQAFLPT SKPSSAYPST TIVNPTIVLL QHNRDPASER RVGEQDSVPT
PAELTSPSRA AERRAKDDSR RVVKSAQDLS DVSMDEVGIP LRNTERSKDW YKTMFKQIHK
LNRDDDSDLH SPRYSYSEDT KSPLSVPRSK SEMNYIDGEK VVKRSATLPL PARSSSLKSS
PERNDWEPPD KKVDTRKYRA EPKSIYEYQP GKSSVLTNEK MSRDISPEEI DLKNEPWYKF
FSELEFGKPT NLEKDLSFSQ AELEADLEKV ETVNKSPSAN PPQSSAISPD VTPEPPGYIY
SSNFHAVKRE PDGTPGVLAS LENERQIYKS VLEGGDIPLQ GLSGLKRPSS SASTKVDRKG
GNAHMISSSS VHSRTFHTSN ALGPGCKHKK PLSAAKACIS EILPSKFKPR LSAPSALLQE
QKSVLLPSEK AQSCENLCVS LSDSKRGLPL RVGGSIENLL MRSRRDYDSR SSSTMSLQEY
GTSARRPCPL SRKAGLHFSM FYRDMHQINR AGLSLGSISS SSVRDLASHF ERSSLALARG
ELGASQEGSE HIPKHTVSSR ITAFEQLIQR SRSMPSLDFS GRLSKSPTPV LSRSGLISAR
SAESLLESTK LRPREIDGMN SGGAFASPTC SNMADHALSF RSLVPSEPHS VCSDELDHCS
NASNDSREGS GGSAHGDFPK HRLNKCKGAC PASYTRFTTI RKHEQQSSRQ PDWRSDSRGD
KNSVLRNIYL MSPLPFRLKK PLQHHPRQPP PNDSSGPPAG QKADLPSQGP QDQPHSAGKP
VVPTRLSSRH TMARLSHNSE PSLDRSAGLE DCTGAINNGN PVPYSDHGLD RNNNPQSELA
AARGDSESPR HFIPADYLES AEEFIRRRHD DKEKLLADQR RLKREQEEAD IAARRHTGVI
PTHHQFITNE RFGDLLNIDD TAKRKSGLEM RPARAKFDFK AQTLKELPLQ KGDIVYIYKQ
IDQNWYEGEH HGRVGIFPRT YIELLPPAEK AQPRKLAPVQ VLEYGEAIAK FNFNGDTQVE
MSFRKGERIT LLRQVDENWY EGRIPGTSRQ GIFPITYVDV LKRPLVKNPV DYIDLPYSSS
PSRSTTASPQ YTSHSKLIMP APSSLPHPRR ALSPEMHAIT SEWISLTVGV PGRRSLAMTP
PLPPLPEASV YDTDHLALSA RVRPSLPLSL PYSSRSDHST LRSVVSPLAL PSPHKAYSLA
PGAQAPLHIN GDGGIHTHQE GFSQPPQGNS DRVISELSDA FSSQSKRQSW REDGSYERRA
ESEAGERYPG GPKISKKNCL RPSDVVRCLS SEQRLSEFHT PDDSQSFKPL GSPFPAWEAG
PPELHRGVEA DRKAAQSGVS QEAVCNEIIN IAEKSVHYCS TVSHPLDFHH KVPPSDSKSS
LIVSQQPQAQ QRRVTPDRSQ TSQDLCSYQA LYSYVPQNDD ELELRDGDIV DVMEKCDDGW
FVGTSRRTRQ FGTFPGNYVK PLYL
//
