ID A0A1U8BVW1_MESAU Unreviewed; 563 AA.
AC A0A1U8BVW1;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=F-box/WD repeat-containing protein 11 isoform X1 {ECO:0000313|RefSeq:XP_012970245.1};
GN Name=Fbxw11 {ECO:0000313|RefSeq:XP_012970245.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012970245.1};
RN [1] {ECO:0000313|RefSeq:XP_012970245.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012970245.1; XM_013114791.2.
DR AlphaFoldDB; A0A1U8BVW1; -.
DR STRING; 10036.ENSMAUP00000003020; -.
DR GeneID; 101831932; -.
DR CTD; 23291; -.
DR OrthoDB; 337075at2759; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
DR GO; GO:1901223; P:negative regulation of non-canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0042753; P:positive regulation of circadian rhythm; IEA:Ensembl.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd22183; F-box_FBXW1B; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 6.10.250.1840; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR021977; Beta-TrCP_D.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14604:SF6; F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B; 1.
DR PANTHER; PTHR14604; WD40 REPEAT PF20; 1.
DR Pfam; PF12125; Beta-TrCP_D; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01028; Beta-TrCP_D; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 150..188
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 257..296
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 297..336
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 337..376
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 380..419
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 420..459
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 460..492
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 509..539
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 563 AA; 64453 MW; AD613DE542FC17EC CRC64;
MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQN TSVMEDQNED
ESPKKSGLWQ ISNGTSSVIV SRKRPSEGNY QKEKDLCIKY FDQWSESDQV EFVEHLISRM
CHYQHGHINS YLKPMLQRDF ITALPEQGLD HIAENILSYL DAKSLCAAEL VCKEWQRVIS
EGMLWKKLIE RMVRTDPLWK GLSERRGWDQ YLFKNRPTDG PPNSFYRSLY PKIIQDIETI
ESNWRCGRHN LQRIQCRSEN SKGVYCLQYD DDKIISGLRD NSIKIWDKTS LECLKVLTGH
TGSVLCLQYD ERVIVTGSSD STVRVWDVNT GEVLNTLIHH NEAVLHLRFS NGLMVTCSKD
RSIAVWDMAS ATDITLRRVL VGHRAAVNVV DFDDKYIVSA SGDRTIKVWS TSTCEFVRTL
NGHKRGIACL QYRDRLVVSG SSDNTIRLWD IECGACLRVL EGHEELVRCI RFDNKRIVSG
AYDGKIKVWD LQAALDPRAP ASTLCLRTLV EHSGRVFRLQ FDEFQIISSS HDDTILIWDF
LNVPPSAQNE TRSPSRTYTY ISR
//
