ID A0A1U8C3R7_MESAU Unreviewed; 258 AA.
AC A0A1U8C3R7;
DT 10-MAY-2017, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Speckle-type POZ protein isoform X2 {ECO:0000313|RefSeq:XP_012973050.2};
GN Name=Spop {ECO:0000313|RefSeq:XP_012973050.2};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_012973050.2};
RN [1] {ECO:0000313|RefSeq:XP_012973050.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26319212;
RA Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT "Transcriptome sequencing and development of an expression microarray
RT platform for liver infection in adenovirus type 5-infected Syrian golden
RT hamsters.";
RL Virology 485:305-312(2015).
RN [2] {ECO:0000313|RefSeq:XP_012973050.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC -!- SIMILARITY: Belongs to the Tdpoz family.
CC {ECO:0000256|ARBA:ARBA00010846}.
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DR RefSeq; XP_012973050.2; XM_013117596.2.
DR AlphaFoldDB; A0A1U8C3R7; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0030163; P:protein catabolic process; IEA:UniProt.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18518; BACK_SPOP; 1.
DR CDD; cd18279; BTB_POZ_SPOP-like; 1.
DR Gene3D; 6.10.250.3030; -; 1.
DR Gene3D; 6.20.250.50; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR034089; SPOP_C.
DR InterPro; IPR008974; TRAF-like.
DR PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR PANTHER; PTHR24413:SF97; SPECKLE-TYPE POZ PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50144; MATH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 1..45
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT DOMAIN 84..146
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 258 AA; 29052 MW; C4BE592E1358E103 CRC64;
MESQRAYRFV QGKDWGFKKF IRRDFLLDEA NGLLPDDKLT LFCEVSVVQD SVNISGQNTM
NMVKVPECRL ADELGGLWEN SRFTDCCLCV AGQEFQAHKA ILAARSPVFS AMFEHEMEES
KKNRVEINDV EPEVFKEMMC FIYTGKAPNL DKMADDLLAA ADKYALERLK VMCEDALCSN
LSVENAAEIL ILADLHSADQ LKTQAVDFIN YHASDVLETS GWKSMVVSHP HLVAEAYRSL
ASAQCPFLGP PRKRLKQS
//
